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   Articles with "polyamine metabolism" as a keyword



Polyamine Metabolism in Climacteric and Non-Climacteric Fruit Ripening.

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recommendations! Published in 2018 at "Methods in molecular biology"

DOI: 10.1007/978-1-4939-7398-9_36

Abstract: Polyamines are small aliphatic amines that are found in both prokaryotic and eukaryotic organisms. These growth regulators have been implicated in abiotic and biotic stresses as well as plant development and morphogenesis. Several studies have… read more here.

Keywords: fruit ripening; polyamine metabolism; fruit; non climacteric ... See more keywords

γ-Aminobutyric acid confers cadmium tolerance in maize plants by concerted regulation of polyamine metabolism and antioxidant defense systems

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recommendations! Published in 2020 at "Scientific Reports"

DOI: 10.1038/s41598-020-59592-1

Abstract: Gamma-Aminobutyric acid (GABA) accumulates in plants following exposure to heavy metals. To investigate the role of GABA in cadmium (Cd) tolerance and elucidate the underlying mechanisms, GABA (0, 25 and 50 µM) was applied to… read more here.

Keywords: maize plants; polyamine metabolism; cadmium tolerance; gaba ... See more keywords

Genome-wide RNAi screen identifies novel players in human 60S subunit biogenesis including key enzymes of polyamine metabolism

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recommendations! Published in 2022 at "Nucleic Acids Research"

DOI: 10.1093/nar/gkac072

Abstract: Abstract Ribosome assembly is an essential process that is linked to human congenital diseases and tumorigenesis. While great progress has been made in deciphering mechanisms governing ribosome biogenesis in eukaryotes, an inventory of factors that… read more here.

Keywords: 60s subunit; polyamine metabolism; wide rnai; enzymes polyamine ... See more keywords

Rebalance of the Polyamine Metabolism Suppresses Oxidative Stress and Delays Senescence in Nucleus Pulposus Cells

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recommendations! Published in 2022 at "Oxidative Medicine and Cellular Longevity"

DOI: 10.1155/2022/8033353

Abstract: Intervertebral disk degeneration (IDD) is a major cause of low back pain that becomes a prevalent age-related disease. However, the pathophysiological processes behind IDD are rarely known. Here, we used bioinformatics analysis based on the… read more here.

Keywords: idd; oxidative stress; polyamine metabolism; metabolism ... See more keywords

Curcumin mediates polyamine metabolism and sensitizes gastrointestinal cancer cells to antitumor polyamine-targeted therapies

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recommendations! Published in 2018 at "PLoS ONE"

DOI: 10.1371/journal.pone.0202677

Abstract: Curcumin, a natural polyphenol that contributes to the flavor and yellow pigment of the spice turmeric, is known for its antioxidant, anti-inflammatory, and anticarcinogenic properties. Capable of affecting the initiation, promotion, and progression of carcinogenesis… read more here.

Keywords: polyamine metabolism; polyamine; cancer cells; cancer ... See more keywords

Application of sucrose modulates the expressions of genes involved in proline and polyamine metabolism in maize seedlings exposed to drought

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recommendations! Published in 2019 at "Biologia plantarum"

DOI: 10.32615/bp.2019.028

Abstract: Sucrose, proline, and polyamines are compatible solutes accumulating in plant tissues and increasing cellular osmolarity under environmental stresses. These compatible solutes and hydrogen peroxide can function as signaling molecules in plants. There has been very… read more here.

Keywords: compatible solutes; polyamine metabolism; drought stress; maize seedlings ... See more keywords

Characterization of polyamine metabolism predicts prognosis, immune profile, and therapeutic efficacy in lung adenocarcinoma patients

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recommendations! Published in 2024 at "Frontiers in Cell and Developmental Biology"

DOI: 10.3389/fcell.2024.1331759

Abstract: Background Polyamine modification patterns in lung adenocarcinoma (LUAD) and their impact on prognosis, immune infiltration, and anti-tumor efficacy have not been systematically explored. Methods Patients from The Cancer Genome Atlas (TCGA) were classified into subtypes… read more here.

Keywords: lung adenocarcinoma; prognosis; pmrs; tumor ... See more keywords

Polyamine metabolism and anti-tumor immunity

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recommendations! Published in 2025 at "Frontiers in Immunology"

DOI: 10.3389/fimmu.2025.1529337

Abstract: Growing attention has been directed toward the critical role of polyamines in the tumor microenvironment and immune regulation. Polyamines, primarily comprising putrescine, spermidine, and spermine, are tightly regulated through coordinated biosynthesis, catabolism, and transport, with… read more here.

Keywords: metabolism anti; metabolism; anti tumor; polyamine metabolism ... See more keywords

c-MYC-Driven Polyamine Metabolism in Ovarian Cancer: From Pathogenesis to Early Detection and Therapy

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recommendations! Published in 2023 at "Cancers"

DOI: 10.3390/cancers15030623

Abstract: Simple Summary This review informs on how the MYC signaling is dysregulated and participates in ovarian cancer progression, and the unmet challenge to directly target MYC for ovarian cancer treatment. Therefore, we proposed to alternatively… read more here.

Keywords: myc; ovarian cancer; cancer; polyamine metabolism ... See more keywords

Light Spectral Composition Modifies Polyamine Metabolism in Young Wheat Plants

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recommendations! Published in 2022 at "International Journal of Molecular Sciences"

DOI: 10.3390/ijms23158394

Abstract: Although light-emitting diode (LED) technology has extended the research on targeted photomorphogenic, physiological, and biochemical responses in plants, there is not enough direct information about how light affects polyamine metabolism. In this study, the effect… read more here.

Keywords: metabolism; spectral composition; polyamine metabolism; light spectral ... See more keywords

Short-Term Salicylic Acid Treatment Affects Polyamine Metabolism Causing ROS–NO Imbalance in Tomato Roots

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recommendations! Published in 2022 at "Plants"

DOI: 10.3390/plants11131670

Abstract: The phytohormone salicylic acid (SA) can influence the polyamine metabolism in plants. Additionally, polyamines (PAs) can regulate the synthesis of SA, providing an exciting interplay between them not only in plant growth and development but… read more here.

Keywords: metabolism; polyamine metabolism; tomato roots; salicylic acid ... See more keywords