From fibrosis to diagnosis: a paediatric case of microscopic polyangiitis and review of the literature
Sign Up to like & getrecommendations! Published in 2017 at "Rheumatology International"
DOI: 10.1007/s00296-017-3923-y
Abstract: We herein describe a case of a 6-year-old girl diagnosed with microscopic polyangiitis (MPA) after a long diagnostic process demanding the cooperation of paediatric respiratory medicine specialists, rheumatologists, nephrologists and radiologist. First symptoms of MPA… read more here.
Keywords: fibrosis; polyangiitis; case; microscopic polyangiitis ... See more keywords
Endothelial dysfunction in patients with granulomatosis with polyangiitis: a case–control study
Sign Up to like & getrecommendations! Published in 2018 at "Rheumatology International"
DOI: 10.1007/s00296-018-4061-x
Abstract: BackgroundGranulomatosis with polyangiitis (GPA) is a rare granulomatous vasculitis affecting small- and medium-sized blood vessels. In optimally treated patients with long-standing disease, the common cause of death is atherosclerosis even in the absence of typical… read more here.
Keywords: dysfunction; dysfunction patients; polyangiitis; fmd ... See more keywords
Disease and treatment-related morbidity in young and elderly patients with granulomatosis with polyangiitis and microscopic polyangiitis.
Sign Up to like & getrecommendations! Published in 2020 at "Seminars in arthritis and rheumatism"
DOI: 10.1016/j.semarthrit.2020.02.008
Abstract: OBJECTIVE Aging may be a risk factor for morbidity in anti-neutrophil cytoplasmic antibody (ANCA)-associated vasculitis (AAV). We compared the rate and better characterized the type of disease- and treatment-related complications affecting young and elderly patients… read more here.
Keywords: polyangiitis; elderly patients; morbidity; treatment related ... See more keywords
Maintaining remission in patients with granulomatosis with polyangiitis or microscopic polyangiitis: the role of ANCA
Sign Up to like & getrecommendations! Published in 2017 at "Expert Opinion on Orphan Drugs"
DOI: 10.1080/21678707.2017.1281123
Abstract: ABSTRACT Introduction: Granulomatosis with Polyangiitis (GPA; formerly Wegener’s) and Microscopic Polyangiitis (MPA) are inflammatory disease entities affecting small to medium vessels. They are characterized by the presence of anti-neutrophil cytoplasmic antibodies (ANCA) and are frequently… read more here.
Keywords: anca; polyangiitis; granulomatosis polyangiitis; role ... See more keywords
Nation-wide survey of the treatment trend of microscopic polyangiitis and granulomatosis with polyangiitis in Japan using the Japanese Ministry of Health, Labour and Welfare Database.
Sign Up to like & getrecommendations! Published in 2021 at "Modern rheumatology"
DOI: 10.1093/mr/roab088
Abstract: OBJECTIVES In Japan, clinical records of patients with intractable diseases, including microscopic polyangiitis (MPA) and granulomatosis with polyangiitis (GPA), are compiled into a database. This study aimed to understand the current treatment status and changes… read more here.
Keywords: survey; microscopic polyangiitis; mpa; gpa ... See more keywords
Incidence of ANCA associated vasculitis and polyarteritis nodosa in Norfolk, UK, from 2011-2020.
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DOI: 10.1093/rheumatology/keaf052
Abstract: OBJECTIVE To report the annual and age-specific incidence of ANCA associated vasculitis and polyarteritis nodosa in the adult population of Norfolk County, UK. METHODS Individuals newly diagnosed with ANCA associated vasculitis or polyarteritis nodosa between… read more here.
Keywords: polyangiitis; polyarteritis nodosa; anca associated; associated vasculitis ... See more keywords
Atypical Conjunctival Lesion as the Initial Presentation of Granulomatosis With Polyangiitis in an Adolescent Male
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DOI: 10.1097/ico.0000000000003015
Abstract: Purpose: The purpose of this study was to report the first case of a conjunctival granulomatous lesion as the presenting sign of granulomatous polyangiitis (GPA) in a pediatric patient. Methods: This study is a case… read more here.
Keywords: atypical conjunctival; presentation; polyangiitis; lesion ... See more keywords
Occult Renal Granulomatous Inflammatory Lesions in Granulomatosis with Polyangiitis Detected by 18F-FDG PET/CT.
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DOI: 10.1097/rlu.0000000000001746
Abstract: A 33-year-old woman with a 7-month history of granulomatosis with polyangiitis F-FDG PET/CT scan due to low-grade intermittent fever and elevation of serum inflammatory markers, which revealed multiple hypermetabolic lesions in bilateral kidneys. Biopsy of… read more here.
Keywords: granulomatosis polyangiitis; polyangiitis; fdg pet; occult renal ... See more keywords
Case report: Two cases of granulomatosis with polyangiitis in long‐term drug‐free remission with rituximab
Sign Up to like & getrecommendations! Published in 2024 at "International Journal of Rheumatic Diseases"
DOI: 10.1111/1756-185x.15395
Abstract: In recent studies on the induction of remission with rituximab in antineutrophil cytoplasmic antibody (ANCA)- associated vasculitis (AAV), such as granulomatosis with polyangiitis (GPA) and microscopic polyangiitis (MPA), the remission rate at 6 months was… read more here.
Keywords: polyangiitis; remission rituximab; term; therapy ... See more keywords
Rituximab pediatric drug development: Pharmacokinetic and pharmacodynamic modeling to inform regulatory approval for rituximab treatment in patients with granulomatosis with polyangiitis or microscopic polyangiitis
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DOI: 10.1111/cts.13351
Abstract: Anti‐neutrophil cytoplasmic antibody‐associated vasculitides granulomatosis with polyangiitis (GPA) and microscopic polyangiitis (MPA) are rare, potentially organ‐ and life‐threatening autoimmune conditions affecting adult and pediatric patients. An open‐label phase II study was conducted to determine safe… read more here.
Keywords: granulomatosis polyangiitis; microscopic polyangiitis; polyangiitis; pediatric patients ... See more keywords
Efficacy and safety of benralizumab in eosinophilic granulomatosis with polyangiitis: A meta‐analysis of eight studies
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DOI: 10.1111/eci.14333
Abstract: Eosinophilic granulomatous polyangiitis (EGPA) is a rare autoimmune disease characterized by multisystemic inflammation, with eosinophils playing a central role in its pathogenesis. Traditional management relies heavily on corticosteroids and immunosuppressants, which are associated with significant… read more here.
Keywords: benralizumab eosinophilic; polyangiitis; safety benralizumab; eosinophilic granulomatosis ... See more keywords