Abstract 5143: Using a multipronged approach to characterize C-terminal domain polybasic motif STK11 variants
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DOI: 10.1158/1538-7445.am2025-5143
Abstract: KRAS-driven lung adenocarcinomas (LUADs) with concurrent STK11 loss of function (LoF) mutations are associated with aggressive tumors with increased risk of metastasis and lower overall and progression free survival. In LUAD, STK11 LoF impacts many… read more here.
Keywords: terminal domain; kinase; polybasic motif; stk11 ... See more keywords