Chemical Investigation of the Indonesian Tunicate Polycarpa aurata and Evaluation of the Effects Against Schistosoma mansoni of the Novel Alkaloids Polyaurines A and B
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DOI: 10.3390/md17050278
Abstract: A deep study of the metabolic content of the tunicate Polycarpa aurata, collected from Indonesian coast, afforded the isolation of two novel alkaloids, polyaurines A (1) and B (2), along with two new p-substituted benzoyl… read more here.
Keywords: alkaloids polyaurines; polycarpa aurata; schistosoma mansoni; novel alkaloids ... See more keywords
Synthesis and Biological Activity of Glycosyl Thiazolyl Disulfides Based on Thiacarpine, an Analogue of the Cytotoxic Alkaloid Polycarpine from the Ascidian Polycarpa aurata
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DOI: 10.3390/md23030117
Abstract: Polycarpine, a diimidazolyl disulfan alkaloid isolated from the ascidian Polycarpa aurata, showed high cytotoxic activity in vitro. However, in vivo experiments have shown that polycarpine has a high acute toxicity. At the same time, its… read more here.
Keywords: polycarpa aurata; ascidian polycarpa; polycarpine; cytotoxic ... See more keywords