No Winter Lasts Forever: Polycomb Complexes Convert Epigenetic Memory of Cold into Flowering.
Sign Up to like & getrecommendations! Published in 2017 at "Developmental cell"
DOI: 10.1016/j.devcel.2017.09.004
Abstract: Two recent papers in Science (Jiang and Berger, 2017 and Yang et al., 2017) reveal that an epigenetic mechanism, mediated by polycomb repressor complex 2 (PRC2), induces flowering after prolonged cold. This repression is biphasic, requiring… read more here.
Keywords: forever polycomb; winter lasts; polycomb complexes; convert epigenetic ... See more keywords
Variant Polycomb complexes in Drosophila consistent with ancient functional diversity
Sign Up to like & getrecommendations! Published in 2022 at "Science Advances"
DOI: 10.1101/2022.04.29.490092
Abstract: Polycomb group (PcG) mutants were first identified in Drosophila based on their failure to maintain proper Hox gene repression during development. The proteins encoded by the corresponding fly genes mainly assemble into one of two… read more here.
Keywords: polycomb; variant polycomb; complexes drosophila; diversity ... See more keywords
Regulation of developmental hierarchy in Drosophila neural stem cell tumors by COMPASS and Polycomb complexes
Sign Up to like & getrecommendations! Published in 2022 at "Science Advances"
DOI: 10.1126/sciadv.abi4529
Abstract: COMPASS and Polycomb complexes are antagonistic chromatin complexes that are frequently inactivated in cancers, but how these events affect the cellular hierarchy, composition, and growth of tumors is unclear. These characteristics can be systematically investigated… read more here.
Keywords: polycomb; stem cell; developmental hierarchy; compass polycomb ... See more keywords
Modulation of the high-order chromatin structure by Polycomb complexes
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Cell and Developmental Biology"
DOI: 10.3389/fcell.2022.1021658
Abstract: The multi-subunit Polycomb Repressive Complex (PRC) 1 and 2 act, either independently or synergistically, to maintain and enforce a repressive state of the target chromatin, thereby regulating the processes of cell lineage specification and organismal… read more here.
Keywords: structure; high order; order chromatin; chromatin ... See more keywords
Roles of Polycomb Complexes in the Reconstruction of 3D Genome Architecture during Preimplantation Embryonic Development
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DOI: 10.3390/genes13122382
Abstract: The appropriate deployment of developmental programs depends on complex genetic information encoded by genomic DNA sequences and their positioning and contacts in the three-dimensional (3D) space within the nucleus. Current studies using novel techniques including,… read more here.
Keywords: developmental programs; pcg; pcg complexes; roles polycomb ... See more keywords
Epigenetic Regulation by Polycomb Complexes from Drosophila to Human and Its Relation to Communicable Disease Pathogenesis
Sign Up to like & getrecommendations! Published in 2022 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms232012285
Abstract: Although all cells in the human body are made of the same DNA, these cells undergo differentiation and behave differently during development, through integration of external and internal stimuli via ‘specific mechanisms.’ Epigenetics is one… read more here.
Keywords: polycomb; regulation polycomb; epigenetic regulation; communicable disease ... See more keywords