homo-Adamantane type polycyclic polyprenylated acylphloroglucinols from Hypericum hookerianum.
Sign Up to like & getrecommendations! Published in 2019 at "Fitoterapia"
DOI: 10.1016/j.fitote.2018.12.014
Abstract: Hookeriones I-Q (1-9), nine new homo-adamantane type polycyclic polyprenylated acylphloroglucinols (PPAPs), were isolated from Hypericum hookerianum, along with twenty known analogues. These structures were determined on the basis of comprehensive NMR and MS spectroscopic data.… read more here.
Keywords: adamantane type; type polycyclic; homo adamantane; hypericum hookerianum ... See more keywords
Diverse Polycyclic Polyprenylated Acylphloroglucinol Congeners with Anti-Nonalcoholic Steatohepatitis Activity from Hypericum forrestii.
Sign Up to like & getrecommendations! Published in 2021 at "Journal of natural products"
DOI: 10.1021/acs.jnatprod.0c01202
Abstract: The new polycyclic polyprenylated acylphloroglucinols, hyperforcinols A-J (1-10), were isolated from the fruits of Hypericum forrestii, together with 30 biogenetic congeners of known structures. The structures of hyperforcinols A-J were determined by HRESIMS and 1D/2D… read more here.
Keywords: polyprenylated acylphloroglucinol; nonalcoholic steatohepatitis; diverse polycyclic; hypericum forrestii ... See more keywords
Longisglucinols A-C, Structurally Intriguing Polycyclic Polyprenylated Acylphloroglucinols with Anti-inflammatory Activity from Hypericum longistylum.
Sign Up to like & getrecommendations! Published in 2020 at "Organic letters"
DOI: 10.1021/acs.orglett.0c02853
Abstract: Longisglucinol A (1), a polycyclic polyprenylated acylphloroglucinol (PPAP) with a new skeleton, along with two new congeners, longisglucinols B (2) and C (3), were isolated from Hypericum longistylum. Compound 1 features an unparalleled 6/6/6/5 fused… read more here.
Keywords: anti inflammatory; inflammatory activity; polycyclic polyprenylated; hypericum longistylum ... See more keywords
Four intricately caged polycyclic polyprenylated acylphloroglucinols from Garcinia multiflora fruits
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DOI: 10.1039/c9qo00586b
Abstract: Garmultinones A–C (1–3), three polycyclic polyprenylated acylphloroglucinols (PPAPs) with a unique caged tricyclo[3.3.1.1.4,8]decane skeleton, and one PPAP garmultinone D (4) with the tricyclo[4.3.1.03,7]decane skeleton bearing the 2,2-dimethyl-3-isopropenylcyclopentyl ring were isolated from the fruits of Garcinia… read more here.
Keywords: polyprenylated acylphloroglucinols; garcinia multiflora; caged polycyclic; four intricately ... See more keywords
Discovery of new polycyclic polyprenylated acylphloroglucinols with diverse architectures as potent cyclooxygenase-2 inhibitors
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DOI: 10.1039/d0qo00259c
Abstract: Cyclooxygenase-2 (COX-2) is a significant therapeutic target of chronic inflammatory diseases. Soniiglucinols A–D (1–4), four new polycyclic polyprenylated acylphloroglucinols (PPAPs) with diverse architectures, were isolated from Hypericum wilsonii. Structurally, 1 and 2 represent the first… read more here.
Keywords: cyclooxygenase; diverse architectures; potent cyclooxygenase; new polycyclic ... See more keywords
Total synthesis and structural reassignment of garcinielliptone FC, a polycyclic polyprenylated acylphloroglucinol with diverse bioactivity.
Sign Up to like & getrecommendations! Published in 2023 at "Chemical communications"
DOI: 10.1039/d3cc01268a
Abstract: Garcinielliptone FC (GFC) was assigned to be a type A polycyclic polyprenylated acylphloroglucinol (PPAP) and was found to exhibit diverse biological activities. Now we revise the structure of GFC to xanthochymol, a type B PPAP,… read more here.
Keywords: garcinielliptone; synthesis structural; polyprenylated acylphloroglucinol; polycyclic polyprenylated ... See more keywords