Polycystic Kidney Disease.
Sign Up to like & getrecommendations! Published in 2017 at "Comprehensive Physiology"
DOI: 10.1002/cphy.c160018
Abstract: Renal cysts, which arise from renal tubules, can be seen in a variety of hereditary and nonhereditary entities. Common mechanisms associated with renal cyst formation include increased cell proliferation, epithelial fluid secretion, and extracellular matrix… read more here.
Keywords: kidney; disease; polycystin; polycystic kidney ... See more keywords
Relationship of Seminal Megavesicles, Prostate Median Cysts, and Genotype in Autosomal Dominant Polycystic Kidney Disease
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Magnetic Resonance Imaging"
DOI: 10.1002/jmri.26289
Abstract: Autosomal dominant polycystic kidney disease (ADPKD) can involve prostate and seminal vesicles but the potential interrelationship of these findings and associations with PKD gene mutation locus and type is unknown. read more here.
Keywords: polycystic kidney; autosomal dominant; dominant polycystic; kidney disease ... See more keywords
Founder mutation in the PMM2 promotor causes hyperinsulinemic hypoglycaemia/polycystic kidney disease (HIPKD).
Sign Up to like & getrecommendations! Published in 2021 at "Molecular genetics & genomic medicine"
DOI: 10.1002/mgg3.1674
Abstract: BACKGROUND Polycystic kidney disease with hyperinsulinaemic hypoglycaemia (HIPKD) is a recently described disease caused by a single nucleotide variant, c.-167G>T, in the promoter region of PMM2 (encoding phosphomannomutase 2), either in homozygosity or compound heterozygosity… read more here.
Keywords: founder; disease; polycystic kidney; mutation ... See more keywords
Polycystic Kidney Disease and Renal Fibrosis.
Sign Up to like & getrecommendations! Published in 2019 at "Advances in experimental medicine and biology"
DOI: 10.1007/978-981-13-8871-2_5
Abstract: Polycystic kidney disease (PKD) is a common genetic disorder characterized by formations of numerous cysts in kidneys and most caused by PKD1 or PKD2 mutations in autosomal dominant polycystic kidney disease (ADPKD). The interstitial inflammation… read more here.
Keywords: renal fibrosis; polycystic kidney; fibrosis; kidney disease ... See more keywords
Insights into autosomal dominant polycystic kidney disease by quantitative mass spectrometry-based proteomics
Sign Up to like & getrecommendations! Published in 2017 at "Cell and Tissue Research"
DOI: 10.1007/s00441-017-2617-9
Abstract: Autosomal dominant polycystic kidney disease (ADPKD) is a common monogenetic disorder that is caused by mutations in the genes PKD1 and PKD2 encoding polycystin-1 and polycystin-2, respectively. Polycystin-1 and -2 form a complex, interact with… read more here.
Keywords: disease; kidney disease; polycystic kidney; autosomal dominant ... See more keywords
Role of apoptosis in the development of autosomal dominant polycystic kidney disease (ADPKD)
Sign Up to like & getrecommendations! Published in 2017 at "Cell and Tissue Research"
DOI: 10.1007/s00441-017-2628-6
Abstract: Autosomal dominant polycystic kidney disease (ADPKD) is a widespread genetic disorder in the Western world and is characterized by cystogenesis that often leads to end-stage renal disease (ESRD). Mutations in the pkd1 gene, encoding for… read more here.
Keywords: apoptosis; disease; autosomal dominant; dominant polycystic ... See more keywords
Expanding the role of vasopressin antagonism in polycystic kidney diseases: From adults to children?
Sign Up to like & getrecommendations! Published in 2017 at "Pediatric Nephrology"
DOI: 10.1007/s00467-017-3672-x
Abstract: Polycystic kidney disease (PKD) encompasses a group of genetic disorders that are common causes of renal failure. The two classic forms of PKD are autosomal recessive polycystic kidney disease (ARPKD) and autosomal dominant polycystic kidney… read more here.
Keywords: kidney; kidney disease; polycystic kidney; adpkd patients ... See more keywords
Relationship between intracranial aneurysms and the severity of autosomal dominant polycystic kidney disease
Sign Up to like & getrecommendations! Published in 2017 at "Acta Neurochirurgica"
DOI: 10.1007/s00701-017-3316-8
Abstract: BackgroundAutosomal dominant polycystic kidney disease (ADPKD) is a hereditary kidney disease characterized by the progressive enlargement of innumerable renal cysts. Although the association of intracranial aneurysms (ICANs) with ADPKD is well known, the relationship between… read more here.
Keywords: kidney; age; disease; polycystic kidney ... See more keywords
Hydrochlorothiazide ameliorates polyuria caused by tolvaptan treatment of polycystic kidney disease in PCK rats
Sign Up to like & getrecommendations! Published in 2018 at "Clinical and Experimental Nephrology"
DOI: 10.1007/s10157-018-1669-9
Abstract: BackgroundTolvaptan is an effective treatment for polycystic kidney disease (PKD), but also causes unfortunate polyuria. Hydrochlorothiazide (HCTZ) has been shown to reduce urine volume in nephrogenic diabetes insipidus, raising the possibility that HCTZ could also… read more here.
Keywords: tolvaptan hctz; hctz; polycystic kidney; treatment polycystic ... See more keywords
Mutation analyses by next-generation sequencing and multiplex ligation-dependent probe amplification in Japanese autosomal dominant polycystic kidney disease patients
Sign Up to like & getrecommendations! Published in 2019 at "Clinical and Experimental Nephrology"
DOI: 10.1007/s10157-019-01736-3
Abstract: BackgroundAutosomal dominant polycystic kidney disease (ADPKD), one of the most common hereditary kidney diseases, causes gradual growth of cysts in the kidneys, leading to renal failure. Owing to the advanced technology of next-generation sequencing (NGS),… read more here.
Keywords: kidney; polycystic kidney; dominant polycystic; next generation ... See more keywords
Effect of tolvaptan on renal involvement in patients with autosomal dominant polycystic kidney disease according to different gene mutations
Sign Up to like & getrecommendations! Published in 2020 at "Clinical and Experimental Nephrology"
DOI: 10.1007/s10157-020-01988-4
Abstract: Autosomal dominant polycystic kidney disease (ADPKD) is an inherited disorder caused by mutations in the polycystic kidney disease (PKD) gene. Although tolvaptan has benefits for renal involvement, the different effects depending on the gene mutation… read more here.
Keywords: polycystic kidney; gene mutation; gene; mutation ... See more keywords