Prevalence of Polycystic Ovary Syndrome in Patients With Pediatric Type 2 Diabetes
Sign Up to like & getrecommendations! Published in 2022 at "JAMA Network Open"
DOI: 10.1001/jamanetworkopen.2021.47454
Abstract: Key Points Question What is the prevalence of polycystic ovary syndrome (PCOS) among adolescents with type 2 diabetes (T2D)? Findings In this systematic review and meta-analysis involving 470 girls across 6 studies, the prevalence of… read more here.
Keywords: polycystic ovary; ovary syndrome; syndrome patients; type diabetes ... See more keywords
Upregulation of the lncRNA SRLR in polycystic ovary syndrome regulates cell apoptosis and IL‐6 expression
Sign Up to like & getrecommendations! Published in 2020 at "Cell Biochemistry and Function"
DOI: 10.1002/cbf.3507
Abstract: Increased levels of interleukin‐6 (IL‐6) contribute to the development of polycystic ovary syndrome (PCOS); in renal cell carcinoma, the long non‐coding RNA (lncRNA) SRLR upregulates IL‐6. In this study, we demonstrated that the levels of… read more here.
Keywords: polycystic ovary; lncrna srlr; cell apoptosis; ovary syndrome ... See more keywords
Dennd1a, a susceptibility gene for polycystic ovary syndrome, is essential for mouse embryogenesis
Sign Up to like & getrecommendations! Published in 2019 at "Developmental Dynamics"
DOI: 10.1002/dvdy.28
Abstract: The DENND1A has been identified as a guanine nucleotide exchange factor for small GTPase Rab35, which functions in endocytic trafficking to mediate the recycling of selective cargos. Genetic alterations within the DENND1A gene have been… read more here.
Keywords: dennd1a susceptibility; ovary syndrome; polycystic ovary; susceptibility gene ... See more keywords
Close correlation between hyperandrogenism and insulin resistance in women with polycystic ovary syndrome—Based on liquid chromatography with tandem mass spectrometry measurements
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Clinical Laboratory Analysis"
DOI: 10.1002/jcla.22699
Abstract: To investigate the correlation between hyperandrogenism (HA) and insulin resistance (IR) in women with polycystic ovary syndrome (PCOS) by measuring serum total testosterone (TT) using a liquid chromatography and tandem mass spectrometry assay (LC‐MS/MS). read more here.
Keywords: women polycystic; polycystic ovary; resistance women; correlation hyperandrogenism ... See more keywords
Impact of lisinopril on cardiometabolic risk factors in sisters of women with polycystic ovary syndrome.
Sign Up to like & getrecommendations! Published in 2023 at "Journal of clinical pharmacology"
DOI: 10.1002/jcph.2268
Abstract: Women with polycystic ovary syndrome (PCOS), the most common endocrinopathy in reproductive age, are characterized by increased cardiometabolic risk. Similar hormonal and metabolic changes were found in their siblings. The purpose of our study was… read more here.
Keywords: polycystic ovary; ovary syndrome; women polycystic; sisters women ... See more keywords
Comparative pharmacokinetics and metabolites study of seven major bioactive components of Shaoyao-Gancao decoction in normal and polycystic ovary syndrome rats by ultra high pressure liquid chromatography with tandem mass spectrometry.
Sign Up to like & getrecommendations! Published in 2019 at "Journal of separation science"
DOI: 10.1002/jssc.201900002
Abstract: A simple and sensitive liquid chromatography with tandem mass spectrometry method was developed for simultaneous quantification of paeoniflorin, albiflorin, oxypaeoniflorin, liquiritin, liquiritigenin, glycyrrhetinic acid, and glycyrrhizin in rat plasma after oral administration of Shaoyao-Gancao decoction,… read more here.
Keywords: shaoyao gancao; ovary syndrome; gancao decoction; polycystic ovary ... See more keywords
Carnosol inhibits KGN cells oxidative stress and apoptosis and attenuates polycystic ovary syndrome phenotypes in mice through Keap1‐mediated Nrf2/HO‐1 activation
Sign Up to like & getrecommendations! Published in 2023 at "Phytotherapy Research"
DOI: 10.1002/ptr.7749
Abstract: Excessive oxidative stress and apoptosis of ovarian granulosa cells lead to abnormal follicular development and ovulation disorders in polycystic ovary syndrome (PCOS). Carnosol is a plant‐derived polyphenol that has been proven to exhibit several cell… read more here.
Keywords: apoptosis; oxidative stress; polycystic ovary; kgn cells ... See more keywords
Exome‐based genome‐wide screening of rare variants associated with the risk of polycystic ovary syndrome
Sign Up to like & getrecommendations! Published in 2023 at "Reproductive Medicine and Biology"
DOI: 10.1002/rmb2.12504
Abstract: Abstract Purpose Genetic factors associated with the risk of polycystic ovary syndrome (PCOS) remain largely unknown. Here, we conducted an optimal sequence kernel association test (SKAT‐O), an exome‐based rare variant association study, to clarify whether… read more here.
Keywords: rare variants; polycystic ovary; ovary syndrome; risk polycystic ... See more keywords
Shapes of the uterine cavity are different in women with polycystic ovary syndrome
Sign Up to like & getrecommendations! Published in 2023 at "Reproductive Medicine and Biology"
DOI: 10.1002/rmb2.12508
Abstract: Abstract Purpose A cross‐sectional study was conducted to evaluate differences in uterine morphology between women with or without polycystic ovary syndrome. Methods The authors recruited 333 infertile reproductive‐age women including 93 with polycystic ovary syndrome… read more here.
Keywords: uterine cavity; shapes uterine; polycystic ovary; ovary syndrome ... See more keywords
Thymoquinone improves folliculogenesis, sexual hormones, gene expression of apoptotic markers and antioxidant enzymes in polycystic ovary syndrome rat model
Sign Up to like & getrecommendations! Published in 2022 at "Veterinary Medicine and Science"
DOI: 10.1002/vms3.958
Abstract: Abstract Background Nowadays, polycystic ovary syndrome (PCOS) is a prevalent cause of infertility affecting women of reproductive age around the world. Thymoquinone is a natural antioxidant, derived from Nigella sativa. Objectives The current study aimed… read more here.
Keywords: thymoquinone; pcos; gene expression; polycystic ovary ... See more keywords
Elevated circulating levels of xenopsin-related peptide-1 are associated with polycystic ovary syndrome
Sign Up to like & getrecommendations! Published in 2017 at "Archives of Gynecology and Obstetrics"
DOI: 10.1007/s00404-017-4493-7
Abstract: PurposeThis study was conducted to compare serum xenopsin-related peptide-1 (XP-1) levels in women with polycystic ovary syndrome (PCOS) and in healthy women and to determine the role of XP-1 levels in PCOS.MethodsForty patients with PCOS… read more here.
Keywords: polycystic ovary; ovary syndrome; xenopsin related; related peptide ... See more keywords