A polycystin-2 protein with modified channel properties leads to an increased diameter of renal tubules and to renal cysts
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DOI: 10.1242/jcs.259013
Abstract: ABSTRACT Mutations in the PKD2 gene cause autosomal-dominant polycystic kidney disease but the physiological role of polycystin-2, the protein product of PKD2, remains elusive. Polycystin-2 belongs to the transient receptor potential (TRP) family of non-selective… read more here.
Keywords: polycystin protein; channel; polycystin; channel properties ... See more keywords