Polydatin protects SH-SY5Y in models of Parkinson's disease by promoting Atg5-mediated but parkin-independent autophagy
Sign Up to like & getrecommendations! Published in 2020 at "Neurochemistry International"
DOI: 10.1016/j.neuint.2020.104671
Abstract: Parkinson's disease (PD), the second most common chronic neurodegenerative disorder, broadly remains incurable. Both genetic susceptibility and exposure to deleterious environmental stimuli contribute to dopaminergic neuron degeneration in the substantia nigra. Hence, reagents that can… read more here.
Keywords: disease; mitochondrial fusion; autophagy; polydatin protects ... See more keywords
Polydatin protects the respiratory system from PM2.5 exposure
Sign Up to like & getrecommendations! Published in 2017 at "Scientific Reports"
DOI: 10.1038/srep40030
Abstract: Atmospheric particle is one of the risk factors for respiratory disease; however, their injury mechanisms are poorly understood, and prevention methods are highly desirable. We constructed artificial PM2.5 (aPM2.5) particles according to the size and… read more here.
Keywords: pm2; apm2; polydatin protects; protects respiratory ... See more keywords
Polydatin protects against gouty nephropathy by inhibiting renal tubular cell pyroptosis
Sign Up to like & getrecommendations! Published in 2022 at "International Journal of Rheumatic Diseases"
DOI: 10.1111/1756-185x.14463
Abstract: To investigate the protective effect and mechanism of polydatin (PD) against gouty nephropathy (GN) in mice. read more here.
Keywords: nephropathy inhibiting; protects gouty; inhibiting renal; renal tubular ... See more keywords