Polyethylene Glycol‐Like Brush Polymer Conjugate of a Protein Drug Does Not Induce an Antipolymer Immune Response and Has Enhanced Pharmacokinetics than Its Polyethylene Glycol Counterpart
Sign Up to like & getrecommendations! Published in 2022 at "Advanced Science"
DOI: 10.1002/advs.202103672
Abstract: Protein therapeutics, except for antibodies, have a short plasma half‐life and poor stability in circulation. Covalent coupling of polyethylene glycol (PEG) to protein drugs addresses this limitation. However, unlike previously thought, PEG is immunogenic. In… read more here.
Keywords: glycol; drug; polyethylene glycol; peg antibodies ... See more keywords
Gellan gum-O,O′-bis(2-aminopropyl)-polyethylene glycol hydrogel for controlled fertilizer release
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Applied Polymer Science"
DOI: 10.1002/app.45636
Abstract: We would like to thank FAPESP, CNPq, and CAPES for their finan-cial support. R. C. Sabadini acknowledges the support provided byCNPq (process 152252/2016-9), and M. M. Silva acknowledges themobility grant provided by CNPq (PVE grant… read more here.
Keywords: gellan gum; gum bis; glycol hydrogel; aminopropyl polyethylene ... See more keywords
Fabrication of bovine serum albumin‐polyethylene glycol nanoparticle conjugated‐folic acid loaded‐naringenin as an efficient carrier biomacromolecule for suppression of cancer cells
Sign Up to like & getrecommendations! Published in 2022 at "Biotechnology and Applied Biochemistry"
DOI: 10.1002/bab.2399
Abstract: Flavonoid compounds play an effective role in cancer suppression and today nanocarriers play an important role in improving the physicochemical properties and transmission of these compounds. In this study, polyethylene glycol‐modified albumin nanoparticles were synthesized… read more here.
Keywords: peg nps; cancer cells; folic acid; polyethylene glycol ... See more keywords
Allergy to polyethylene glycol and polysorbates in a patient cohort: Diagnostic work‐up and decision points for vaccination during the COVID‐19 pandemic
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DOI: 10.1002/clt2.12111
Abstract: Abstract Background During the COVID‐19 pandemic focus has been on polyethylene glycol (PEG) and polysorbate as these excipients are constituents in the first vaccines and possible elicitors of allergic reactions to the vaccines. We aimed… read more here.
Keywords: allergy; polyethylene glycol; decision points; peg polysorbate ... See more keywords
Dopamine Functionalized Polyethylene Glycol for Improving Stability of Gold Nanoparticles Against Reactive Oxygen Species in Serum.
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DOI: 10.1002/marc.202200035
Abstract: PEGylation is the most effective antifouling method for the surface modification of gold nanoparticles (AuNPs). However, thiol-terminated polyethylene glycol (HS-PEG) ligands tethered on the AuNPs are instable in serum and can detach from the AuNP… read more here.
Keywords: reactive oxygen; gold nanoparticles; oxygen species; polyethylene glycol ... See more keywords
Problems and solutions of polyethylene glycol co-injection method in multiresidue pesticide analysis by gas chromatography-mass spectrometry: evaluation of instability phenomenon in type II pyrethroids and its suppression by novel analyte protectants
Sign Up to like & getrecommendations! Published in 2018 at "Analytical and Bioanalytical Chemistry"
DOI: 10.1007/s00216-018-1002-1
Abstract: AbstractPolyethylene glycol 300 is commonly used as a base material for “analyte protection” in multiresidue pesticide analysis via gas chromatography-mass spectrometry. However, the disadvantage of the co-injection method using polyethylene glycol 300 is that it… read more here.
Keywords: pesticide analysis; multiresidue pesticide; polyethylene glycol; type pyrethroids ... See more keywords
Polyethylene glycol crowding effect on hyaluronidase activity monitored by capillary electrophoresis
Sign Up to like & getrecommendations! Published in 2020 at "Analytical and Bioanalytical Chemistry"
DOI: 10.1007/s00216-020-02659-9
Abstract: To mimic the activity of hyaluronidase in natural environment, the hydrolysis of hyaluronic acid (HA) by hyaluronidase was investigated for the first time in the presence of crowding agents using capillary electrophoresis (CE) as a… read more here.
Keywords: capillary electrophoresis; hyaluronidase; hyaluronidase activity; effect ... See more keywords
Rheological investigation of the viscoelastic thixotropic behavior of synthesized polyethylene glycol-modified polyacrylamide hydrogels using different accelerators
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DOI: 10.1007/s00289-020-03163-x
Abstract: The present work is mainly focused on the synthesis and comprehensive rheological investigation of uniform and large macroporous polyethylene glycol-modified polyacrylamide hydrogels [PEG-m-P(AAm)] through free radical polymerization using different accelerators (ascorbic acid (AsA), thermal activation… read more here.
Keywords: glycol modified; polyethylene glycol; rheological investigation; modified polyacrylamide ... See more keywords
Assessment of changes in growth traits, oxidative stress parameters, and enzymatic and non-enzymatic antioxidant defense mechanisms in Lepidium draba plant under osmotic stress induced by polyethylene glycol
Sign Up to like & getrecommendations! Published in 2019 at "Protoplasma"
DOI: 10.1007/s00709-019-01457-0
Abstract: Lepidium draba is a weed with the medicinal properties which few researches have been done on it. In this study, some traits, related to the osmotic stress, in 14-day-old L. draba sprouts that were grown… read more here.
Keywords: peroxidase; osmotic stress; stress; polyethylene glycol ... See more keywords
Retention Behavior of Polyethylene Glycol and Its Influence on Protein Elution on Hydrophobic Interaction Chromatography Media
Sign Up to like & getrecommendations! Published in 2018 at "Chromatographia"
DOI: 10.1007/s10337-018-3635-9
Abstract: The retention behavior of polyethylene glycol (PEG) on different types of hydrophobic interaction chromatography (HIC) resins containing butyl, octyl, and phenyl ligands was analyzed. An incomplete elution or splitting of the polymer peak into two… read more here.
Keywords: protein; behavior polyethylene; hydrophobic interaction; retention behavior ... See more keywords
Silver nanoparticles supported on polyethylene glycol/cellulose acetate ultrafiltration membranes: preparation and characterization of composite
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DOI: 10.1007/s10570-017-1471-y
Abstract: In this research work, silver nanoparticles/polyethylene glycol/cellulose acetate ultrafiltration (Ag-NPs/PEG/CA UF) composite membranes were synthesized and characterized. The Ag-NPs were embedded in the polymer matrix by two methods: in situ and ex situ; varying the… read more here.
Keywords: silver nanoparticles; nps; polyethylene glycol; spectroscopy ... See more keywords