Polygenic hazard score, amyloid deposition and Alzheimer’s neurodegeneration
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DOI: 10.1093/brain/awy327
Abstract: Mounting evidence indicates that the polygenic basis of late-onset Alzheimer's disease can be harnessed to identify individuals at greatest risk for cognitive decline. We have previously developed and validated a polygenic hazard score comprising of… read more here.
Keywords: polygenic hazard; hazard; volume; hazard scores ... See more keywords
Linear Mixed Model Analysis of Polygenic Hazard Score on Verbal Memory Decline in Alzheimer’s Disease
Sign Up to like & getrecommendations! Published in 2022 at "Nursing Research"
DOI: 10.1097/nnr.0000000000000623
Abstract: Background Alzheimer’s disease (AD) is a chronic, progressive, degenerative disease characterized by cognitive dysfunction, including verbal memory loss. Studies were lacking in examining the longitudinal effect of polygenic hazard score on the Rey Auditory Verbal… read more here.
Keywords: verbal memory; disease; polygenic hazard; hazard score ... See more keywords