Monogenic, polygenic, and oligogenic familial hypercholesterolemia
Sign Up to like & getrecommendations! Published in 2019 at "Current Opinion in Lipidology"
DOI: 10.1097/mol.0000000000000609
Abstract: Purpose of reviewFamilial hypercholesterolemia has long been considered a monogenic disorder. However, recent advances in genetic analyses have revealed various forms of this disorder, including polygenic and oligogenic familial hypercholesterolemia. We review the current understanding… read more here.
Keywords: familial hypercholesterolemia; oligogenic familial; hypercholesterolemia; monogenic polygenic ... See more keywords
Update on Genetic Basis of Brugada Syndrome: Monogenic, Polygenic or Oligogenic?
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DOI: 10.3390/ijms21197155
Abstract: Brugada syndrome is a rare inherited arrhythmogenic disease leading to ventricular fibrillation and high risk of sudden death. In 1998, this syndrome was linked with a genetic variant with an autosomal dominant pattern of inheritance.… read more here.
Keywords: disease; brugada syndrome; polygenic oligogenic; update genetic ... See more keywords