A machine-learning heuristic to improve gene score prediction of polygenic traits
Sign Up to like & getrecommendations! Published in 2017 at "Scientific Reports"
DOI: 10.1038/s41598-017-13056-1
Abstract: Machine-learning techniques have helped solve a broad range of prediction problems, yet are not widely used to build polygenic risk scores for the prediction of complex traits. We propose a novel heuristic based on machine-learning… read more here.
Keywords: machine learning; prediction polygenic; polygenic traits; score ... See more keywords
A population‐genomic approach for estimating selection on polygenic traits in heterogeneous environments
Sign Up to like & getrecommendations! Published in 2021 at "Molecular Ecology Resources"
DOI: 10.1111/1755-0998.13371
Abstract: Strong selection can cause rapid evolutionary change, but temporal fluctuations in the form, direction and intensity of selection can limit net evolutionary change over longer time periods. Fluctuating selection could affect molecular diversity levels and… read more here.
Keywords: selection polygenic; method; selection; population genomic ... See more keywords