A polygenic two-hit hypothesis for prostate cancer.
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DOI: 10.1093/jnci/djad001
Abstract: Prostate cancer is one of the most heritable cancers. Hundreds of germline polymorphisms have been linked to prostate cancer diagnosis and prognosis. Polygenic risk scores can predict genetic risk of a prostate cancer diagnosis. While… read more here.
Keywords: two hit; prostate cancer; polygenic two; risk ... See more keywords