AAV-Mediated Artificial miRNA Reduces Pathogenic Polyglucosan Bodies and Neuroinflammation in Adult Polyglucosan Body and Lafora Disease Mouse Models
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DOI: 10.1007/s13311-022-01218-7
Abstract: Adult polyglucosan body disease (APBD) and Lafora disease (LD) are autosomal recessive glycogen storage neurological disorders. APBD is caused by mutations in the glycogen branching enzyme ( GBE1 ) gene and is characterized by progressive… read more here.
Keywords: glycogen; adult polyglucosan; polyglucosan bodies; disease ... See more keywords
Polyglucosan Bodies in the Prostatic Stromal Smooth Muscles of Aged Dogs.
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DOI: 10.14670/hh-11-818
Abstract: Polyglucosan bodies (PGB) in the prostate of aged dogs without neurological signs were examined by light microscopy, histochemistry and immunohistochemistry. Prostatic PGB were round or oval and slightly basophilic. Most of the bodies were situated… read more here.
Keywords: bodies prostatic; prostatic stromal; pgb; aged dogs ... See more keywords
Pathomorphogenesis of Glycogen-Ground Glass Hepatocytic Inclusions (Polyglucosan Bodies) in Children after Liver Transplantation
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DOI: 10.3390/ijms23179996
Abstract: Seventeen out of 764 liver biopsies from transplanted (Tx) livers in children showed glycogen-ground glass (GGG) hepatocytic inclusions. The inclusions were not present in pre-Tx or in the explanted or donor’s liver. Under the electron… read more here.
Keywords: hepatocytic inclusions; glycogen ground; ground glass; polyglucosan bodies ... See more keywords