Bacterial pseudokinase catalyzes protein polyglutamylation to inhibit the SidE-family ubiquitin ligases
Sign Up to like & getrecommendations! Published in 2019 at "Science"
DOI: 10.1126/science.aaw7446
Abstract: Divergent protein kinase SidJ is a protein produced by Legionella pneumophila that orchestrates this intracellular pathogen's establishment within the host cell. SidJ prevents lysosome fusion with the vacuole, within which the bacterium resides and replicates.… read more here.
Keywords: family ubiquitin; ubiquitin ligases; polyglutamylation; host ... See more keywords
Microtubule polyglutamylation is important for regulating cytoskeletal architecture and motility in Trypanosoma brucei
Sign Up to like & getrecommendations! Published in 2020 at "Journal of Cell Science"
DOI: 10.1242/jcs.248047
Abstract: ABSTRACT The shape of kinetoplastids, such as Trypanosoma brucei, is precisely defined during the stages of the life cycle and governed by a stable subpellicular microtubule cytoskeleton. During the cell cycle and transitions between life… read more here.
Keywords: microtubule; microtubule polyglutamylation; trypanosoma brucei; polyglutamylation ... See more keywords