Polyglycerol for Half-Life Extension of Proteins-Alternative to PEGylation?
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DOI: 10.1021/acs.biomac.0c01627
Abstract: Since several decades, PEGylation is known to be the clinical standard to enhance pharmacokinetics of biotherapeutics. In this study, we introduce polyglycerol (PG) of different lengths and architectures (linear and hyperbranched) as an alternative polymer… read more here.
Keywords: polyglycerol half; life; life extension; half life ... See more keywords