Aqueous extract of Polygonatum sibiricum ameliorates glucose and lipid metabolism via PI3K/AKT signaling pathway in high-fat diet and streptozotocin-induced diabetic mice.
Sign Up to like & getrecommendations! Published in 2022 at "Journal of food biochemistry"
DOI: 10.1111/jfbc.14402
Abstract: This study was aimed to investigate the protective effects and elucidate the mechanisms of aqueous extract of Polygonatum sibiricum (PSAE) on glucolipid metabolism during the development of type 2 diabetes (T2DM). C57BL/6J mice fed with… read more here.
Keywords: aqueous extract; metabolism; polygonatum sibiricum; glucose lipid ... See more keywords
Polygonatum sibiricum Polysaccharides Protect against MPP-Induced Neurotoxicity via the Akt/mTOR and Nrf2 Pathways
Sign Up to like & getrecommendations! Published in 2021 at "Oxidative Medicine and Cellular Longevity"
DOI: 10.1155/2021/8843899
Abstract: Polygonatum sibiricum, a well-known life-prolonging tonic in Chinese medicine, has been widely used for nourishing nerves in the orient, but the underlying molecular mechanisms remain unclear. In this study, we found that P. sibiricum polysaccharides… read more here.
Keywords: mpp induced; medicine; sibiricum polysaccharides; akt mtor ... See more keywords
SSR Loci Analysis in Transcriptome and Molecular Marker Development in Polygonatum sibiricum
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DOI: 10.1155/2022/4237913
Abstract: To study the SSR loci information and develop molecular markers, a total of 435,858 unigenes in transcriptome of Polygonatum sibiricum were used to explore SSR. The distribution frequency of SSR and the basic characteristics of… read more here.
Keywords: ssr; ssr loci; polygonatum sibiricum; analysis ... See more keywords
Cloning and Characterization of the Gene Encoding HMGS Synthase in Polygonatum sibiricum
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DOI: 10.1155/2022/7441296
Abstract: The saponins of Polygonatum sibiricum had many pharmacological activities such as antitumor, antioxidation, and blood sugar lowering, which were synthesized by two pathways: mevalonate (MVA) and methylerythritol phosphate (MEP). 3-Hydroxy-3-methylglutaryl coenzyme A synthase (HMGS) was… read more here.
Keywords: polygonatum sibiricum; synthase; characterization gene; sibiricum ... See more keywords
Chemical composition analysis and biofunctionality of Polygonatum sibiricum and Polygonatum odoratum extracts
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DOI: 10.15376/biores.18.2.3608-3619
Abstract: Polygonatum sibiricum (P. sibiricum) and Polygonatum odoratum (P. odoratum) are commonly known Chinese herbal medicine sources. Although they had similar medical effects, the difference between these varieties was verified in this study. Liquid chromatography with… read more here.
Keywords: polygonatum sibiricum; polygonatum; odoratum; analysis ... See more keywords
Synthesis of naphthalimide-type chemsensor and its application in quality evaluation for polygonatum sibiricum Red
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Chemistry"
DOI: 10.3389/fchem.2022.969014
Abstract: The premise and key of ensuring the safety and effectiveness of traditional Chinese medicine (TCM) is to construct appropriate quality evaluation system of TCM. This study aimed to establish a pre-column derivatization HPLC method for… read more here.
Keywords: sibiricum; polygonatum sibiricum; quality evaluation; quality ... See more keywords
Blood-Enriching Effects and Immune-Regulation Mechanism of Steam-Processed Polygonatum Sibiricum Polysaccharide in Blood Deficiency Syndrome Mice
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DOI: 10.3389/fimmu.2022.813676
Abstract: Polygonatum sibiricum Red. has been used as a medicinal herb and nutritional food in traditional Chinese medicine for a long time. It must be processed prior to clinical use for safe and effective applications. However,… read more here.
Keywords: polygonatum; polygonatum sibiricum; enriching effects; blood enriching ... See more keywords
Advances in Polygonatum sibiricum polysaccharides: Extraction, purification, structure, biosynthesis, and bioactivity
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DOI: 10.3389/fnut.2022.1074671
Abstract: Polygonatum sibiricum has been used as food and medicine for thousands of years, and P. sibiricum polysaccharides (PSPs) have become the hot research spot due to their various health-promoting functions. Numerous studies have shown that… read more here.
Keywords: polygonatum sibiricum; extraction purification; structure; sibiricum polysaccharides ... See more keywords
Anti-cancer Potential of Polysaccharide Extracted From Polygonatum sibiricum on HepG2 Cells via Cell Cycle Arrest and Apoptosis
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DOI: 10.3389/fnut.2022.938290
Abstract: Polygonatum sibiricum is one of the most widely used traditional Chinese medicine in China. Polygonatum sibiricum polysaccharide (PSP) is the main functional component of Polygonatum sibiricum. In this study, a water-soluble polysaccharide (PSP-1) was first… read more here.
Keywords: cell; polygonatum sibiricum; psp; spectroscopy ... See more keywords
Benefits of neutral polysaccharide from rhizomes of Polygonatum sibiricum to intestinal function of aged mice
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DOI: 10.3389/fnut.2022.992102
Abstract: One purified neutral polysaccharide fraction was obtained from the rhizome of Polygonatum sibiricum by DEAE ion exchange and gel chromatography. Structure elucidation was performed by methanolysis, methylation, FT-IR, and NMR. The results indicated that PSP-NP… read more here.
Keywords: neutral polysaccharide; polygonatum sibiricum; function aged; aged mice ... See more keywords
Metabolome and transcriptome signatures shed light on the anti-obesity effect of Polygonatum sibiricum
Sign Up to like & getrecommendations! Published in 2023 at "Frontiers in Plant Science"
DOI: 10.3389/fpls.2023.1181861
Abstract: Obesity has become one of the major threats to human health across the globe. The rhizomes of Polygonatum sibiricum have shown promising anti-obesity effect. However, the metabolic and genetic basis mediating this beneficial effect are… read more here.
Keywords: polygonatum sibiricum; obesity effect; anti obesity; acid ... See more keywords