Polymyxin B-Polysaccharide Polyion Nanocomplex with Improved Biocompatibility and Unaffected Antibacterial Activity for Acute Lung Infection Management.
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DOI: 10.1002/adhm.201901542
Abstract: The decade-old antibiotic, polymyxin B (PMB), is regarded as the last line defense against gram-negative "superbug." However, the serious nephrotoxicity and neurotoxicity strongly obstruct further application of this highly effective antibiotic. Herein, a charge switchable… read more here.
Keywords: antibacterial activity; pmb; polyion nanocomplex; acute lung ... See more keywords