Polymeric micelles with aggregation-induced emission based on microbial ε-polylysine for doxorubicin delivery
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DOI: 10.1016/j.eurpolymj.2019.109355
Abstract: Abstract Natural polymers have shown special advantages in application as drug delivery carriers. However, microbial e-polylysine seems to have been snubbed. In this study, we constructed a drug delivery system based on natural e-polylysine. Amphipathic… read more here.
Keywords: microbial polylysine; delivery; aggregation induced; polylysine ... See more keywords
Functionalized polylysine biomaterials for advanced medical applications: A review
Sign Up to like & getrecommendations! Published in 2021 at "European Polymer Journal"
DOI: 10.1016/j.eurpolymj.2020.110248
Abstract: Abstract Advancements in the biomedical sector are dominating due to evolutions in healthcare functions such as targeted drug and gene delivery, bio-adhesives for tissue transplantation, bio-fibers based wound dressing, and protein immobilization. Among the various… read more here.
Keywords: advanced medical; medical applications; polylysine; biomaterials advanced ... See more keywords
Characteristics and bioactive functions of chitosan/gelatin-based film incorporated with ε-polylysine and astaxanthin extracts derived from by-products of shrimp (Litopenaeus vannamei)
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DOI: 10.1016/j.foodhyd.2019.105436
Abstract: Abstract A biofunctional composite film was prepared using a casting method by incorporation of e-polylysine (e-PL) plus astaxanthin (Asta) extracts from Litopenaeus vannamei (L. vannamei) by-products into chitosan and gelatin film forming formulations. Compared with… read more here.
Keywords: litopenaeus vannamei; microscopy; polylysine; composite film ... See more keywords
Physical properties and antibacterial activity of the composited films based on carboxymethyl cellulose and gelatin functionalized with ε-polylysine.
Sign Up to like & getrecommendations! Published in 2021 at "International journal of biological macromolecules"
DOI: 10.1016/j.ijbiomac.2021.09.181
Abstract: Antibacterial composite films were produced from carboxymethyl cellulose-gelatin (CMC-Gel) blend with different concentration of ε-polylysine (ε-PL) and their physical and chemical properties were characterized. Compared with the control CMC-Gel film, the functionalized films had almost… read more here.
Keywords: cellulose gelatin; polylysine; carboxymethyl cellulose; antibacterial activity ... See more keywords
Enzyme-Mimicking Materials from Designed Self-Assembly of Lysine-Rich Peptides and G-Quadruplex DNA/Hemin DNAzyme: Charge Effect of the Key Residues on the Catalytic Functions.
Sign Up to like & getrecommendations! Published in 2022 at "Biomacromolecules"
DOI: 10.1021/acs.biomac.2c00620
Abstract: In enzymatic active sites, the essential functional groups are spatially arranged as a result of the enzyme three-dimensional folding, which leads to remarkable catalytic properties. We are inspired to self-assemble the polylysine peptides with guanine-rich… read more here.
Keywords: key residues; polylysine dna; polylysine; hemin ... See more keywords
Charge-Reversible Pro-Ribonuclease Enveloped in Virus-like Synthetic Nanocapsules for Systemic Treatment of Intractable Glioma.
Sign Up to like & getrecommendations! Published in 2022 at "ACS applied materials & interfaces"
DOI: 10.1021/acsami.2c03763
Abstract: We have tailored multifaceted chemistries into the manufacture of artificial virus-like delivery vehicles mimicking viral "intelligent" transportation pathways through sequential biological barriers; these vehicles can acquire the ability to dynamically "program transfer" to their target… read more here.
Keywords: charge reversible; polylysine; pro proteins; virus like ... See more keywords
Dietary ε-Polylysine Affects on Gut Microbiota and Plasma Metabolites Profiling in Mice
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Nutrition"
DOI: 10.3389/fnut.2022.842686
Abstract: Given the antibacterial effects of ε-polylysine acting on cell membranes, and that glycerol phospholipids are important components of the cell membrane, we hypothesized that ε-polylysine may regulate glycerophospholipid metabolism by modifying the gut microbiota. To… read more here.
Keywords: affects gut; gut microbiota; polylysine affects; lachnospiraceae ucg ... See more keywords