Tuning the Hydrophilic - Hydrophobic Balance of Molecular Polymer Bottlebrushes Enhances their Tumor Homing Properties.
Sign Up to like & getrecommendations! Published in 2022 at "Advanced healthcare materials"
DOI: 10.1002/adhm.202200163
Abstract: Nanoparticle (NP)-based drug delivery systems are promising in anti-cancer therapy, capable of delivering cargo with superior selectivity and achieving enhanced tumor accumulation compared to small-molecule therapeutics. As more efforts are being devoted to NP development,… read more here.
Keywords: tumor; hydrophilic hydrophobic; molecular polymer; hydrophobic balance ... See more keywords
Molecular polymer bottlebrushes in nanomedicine: therapeutic and diagnostic applications.
Sign Up to like & getrecommendations! Published in 2022 at "Chemical communications"
DOI: 10.1039/d2cc01601j
Abstract: Molecular polymer bottlebrushes are densely grafted, individual macromolecules with nanoscale proportions. The last decade has seen an increased focus on this material class, especially in nanomedicine and for biomedical applications. This Feature Article provides an… read more here.
Keywords: therapeutic diagnostic; bottlebrushes nanomedicine; nanomedicine therapeutic; polymer bottlebrushes ... See more keywords
Synthesis of Poly(N-vinylpyrrolidone)-Based Polymer Bottlebrushes by ATRPA and RAFT Polymerization: Toward Drug Delivery Application
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DOI: 10.3390/polym11061079
Abstract: Atom transfer radical polyaddition (ATRPA) was utilized herein to synthesize a specific functional polyester. We conducted ATRPA of 4-vinylbenzyl 2-bromo-2-phenylacetate (VBBPA) inimer and successfully obtained a linear type poly(VBBPA) (PVBBPA) polyester with benzylic bromides along… read more here.
Keywords: polymer bottlebrushes; polymer; toward drug; poly ... See more keywords