A bispecific peptide-polymer conjugate bridging target-effector cells to enhance immunotherapy.
Sign Up to like & getrecommendations! Published in 2023 at "Advanced healthcare materials"
DOI: 10.1002/adhm.202202977
Abstract: Peptide-based immune checkpoint inhibitors exhibited remarkable therapeutic benefits although their application was hindered by quick blood clearance and low affinity with receptors. The modification of the peptides into artificial antibodies was an ideal platform to… read more here.
Keywords: polymer conjugate; immunotherapy; bispecific peptide; effector cells ... See more keywords
Synthesis of 5-Fluorouracil Polymer Conjugate and 19F NMR Analysis of Drug Release for MRI Monitoring
Sign Up to like & getrecommendations! Published in 2023 at "Polymers"
DOI: 10.3390/polym15071778
Abstract: To monitor the release of fluorinated drugs from polymeric carriers, a novel 19F MRI enzyme-responsive contrast agent was developed and tested. This contrast agent was prepared by conjugation of 5-fluorouracil (5-FU) to hyperbranched poly(N,N-dimethylacrylamide) (HB-PDMA)… read more here.
Keywords: polymer conjugate; 19f nmr; mri; release ... See more keywords