Articles with "polymer conjugates" as a keyword



Scalable Approach to Molecular Motor‐Polymer Conjugates for Light‐Driven Artificial Muscles

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Published in 2024 at "Advanced Materials"

DOI: 10.1002/adma.202403514

Abstract: The integration of molecular machines and motors into materials represents a promising avenue for creating dynamic and functional molecular systems, with potential applications in soft robotics or reconfigurable biomaterials. However, the development of truly scalable… read more here.

Keywords: artificial muscles; polymer conjugates; polymer; light driven ... See more keywords
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Synthesis and Applications of Protein/Peptide‐Polymer Conjugates

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Published in 2017 at "Macromolecular Chemistry and Physics"

DOI: 10.1002/macp.201600595

Abstract: Recent advances in synthetic methodologies have brought us closer than ever to the precision conferred by nature. For example, the control possible in reversible deactivation radical polymerization enables us to design and synthesize macromolecules with… read more here.

Keywords: applications protein; polymer conjugates; peptide polymer; polymer ... See more keywords

One-Pot Synthesis of Thermoresponsive Amyloidogenic Peptide-Polymer Conjugates via Thio-Bromo "Click" Reaction of RAFT Polymers.

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Published in 2018 at "Macromolecular rapid communications"

DOI: 10.1002/marc.201700507

Abstract: A synthetic strategy to efficiently prepare main-chain peptide-polymer conjugates probing their aggregation in solution is described. An in situ tandem reaction based on aminolysis/thio-bromo "click" reaction is performed to tether an amyloidogenic peptide fragment amyloid-β17-20… read more here.

Keywords: polymer conjugates; peptide polymer; polymer; reaction ... See more keywords

Engineering Thermoresponsive Enzyme-Polymer Conjugates via Glycan-Selective In Situ Polymerization for Recyclable Homogeneous Biocatalysis.

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Published in 2024 at "Biomacromolecules"

DOI: 10.1021/acs.biomac.4c01220

Abstract: Enzymes are crucial for various technological applications, but their inherent instability and short lifespan pose challenges. This study presents facile immobilized enzyme technology with the development of thermoresponsive enzyme-polymer conjugates (EPCs), using glucose oxidase (GOx)… read more here.

Keywords: enzyme polymer; polymer conjugates; enzyme; thermoresponsive enzyme ... See more keywords

Protein-Polymer Conjugates as Biocompatible and Recyclable ATRP Catalysts.

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Published in 2025 at "Biomacromolecules"

DOI: 10.1021/acs.biomac.4c01342

Abstract: Atom transfer radical polymerization (ATRP) is a leading method for creating polymers with precise control over molecular weight, yet its reliance on metal catalysts limits its application in metal-sensitive and environmental contexts. Addressing these limitations,… read more here.

Keywords: atrp; polymer conjugates; recyclable atrp; protein polymer ... See more keywords

Intramolecular Interactions of Conjugated Polymers Mimic Molecular Chaperones to Stabilize Protein-Polymer Conjugates.

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Published in 2018 at "Biomacromolecules"

DOI: 10.1021/acs.biomac.8b00927

Abstract: The power and elegance of protein-polymer conjugates has solved many vexing problems for society. Rational design of these complex covalent hybrids depends on a deep understanding of how polymer physicochemical properties impact the conjugate structure-function-dynamic… read more here.

Keywords: interactions conjugated; polymer conjugates; conjugated polymers; protein polymer ... See more keywords

Improved Ordering in Low Molecular Weight Protein-Polymer Conjugates Through Oligomerization of the Protein Block.

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Published in 2018 at "Biomacromolecules"

DOI: 10.1021/acs.biomac.8b00928

Abstract: The self-assembly of protein-polymer conjugates incorporating oligomers of a small, engineered high-affinity binding protein, rcSso7d.SA, is studied to determine the effect of protein oligomerization on nanoscale ordering. Oligomerization enables a systematic increase in the protein… read more here.

Keywords: protein; block; polymer conjugates; oligomerization protein ... See more keywords

DNA-Polymer Conjugates by Photoinduced RAFT Polymerization.

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Published in 2019 at "Biomacromolecules"

DOI: 10.1021/acs.biomac.8b01328

Abstract: Conventional grafting-to approaches to DNA-polymer conjugates are often limited by low reaction yields due to the sterically hindered coupling of a presynthesized polymer to DNA. The grafting-from strategy, in contrast, allows one to directly graft… read more here.

Keywords: polymer conjugates; dna; dna polymer; polymer ... See more keywords

Charge-Preserving Atom Transfer Radical Polymerization Initiator Rescues the Lost Function of Negatively Charged Protein-Polymer Conjugates.

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Published in 2019 at "Biomacromolecules"

DOI: 10.1021/acs.biomac.9b00379

Abstract: When grown from the surface of proteins, negatively charged polymers cause irreversible inactivation, thereby limiting the breadth of the synthetic space that negatively charged protein-polymer conjugates can be applied to. More broadly speaking, independent of… read more here.

Keywords: negatively charged; charged protein; initiator; polymer conjugates ... See more keywords
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Pyridyl Disulfide Reaction Chemistry: An Efficient Strategy toward Redox-Responsive Cyclic Peptide–Polymer Conjugates

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Published in 2019 at "ACS Macro Letters"

DOI: 10.1021/acsmacrolett.9b00538

Abstract: Cyclic peptide–polymer conjugates are capable of self-assembling into supramolecular polymeric nanotubes driven by the strong multiple hydrogen bonding interactions between the cyclic peptides. In ... read more here.

Keywords: polymer conjugates; cyclic peptide; chemistry; pyridyl disulfide ... See more keywords

Hypoxia Reversion by Low-Immunogenic Ultra-Acid-Sensitive Comicelles of Protein-Polymer Conjugates Sensitizes Tumors to Photodynamic Therapy.

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Published in 2024 at "Journal of the American Chemical Society"

DOI: 10.1021/jacs.3c13501

Abstract: Hypoxia is characteristic of the tumor microenvironment, which is correlated with resistance to photodynamic therapy (PDT), radiotherapy, chemotherapy, and immunotherapy. Catalase is potentially useful to catalyze the conversion of endogenous H2O2 to O2 for hypoxia… read more here.

Keywords: polymer conjugates; hypoxia; acid sensitive; hypoxia reversion ... See more keywords