Triggered ferroptotic polymer micelles for reversing multidrug resistance to chemotherapy.
Sign Up to like & getrecommendations! Published in 2019 at "Biomaterials"
DOI: 10.1016/j.biomaterials.2019.119486
Abstract: Drug-tolerant persister cancer cells (PCCs) play an important role in the development of multidrug resistance (MDR) to anti-cancer drugs. This is due to the strong link between PCCs formation and epithelial-mesenchymal transition (EMT), as well… read more here.
Keywords: triggered ferroptotic; mdr; polymer micelles; ferroptotic polymer ... See more keywords
Enhancing the performance of PEG-b-PCL copolymers as precursors of micellar vehicles for amphotericin B through its conjugation with cholesterol
Sign Up to like & getrecommendations! Published in 2019 at "Colloids and Surfaces A: Physicochemical and Engineering Aspects"
DOI: 10.1016/j.colsurfa.2019.03.086
Abstract: Abstract Amphotericin B (AmB) is an antifungal drug with a broad spectrum of action. It has few resistance reports, and it is widely used for treating invasive fungal infections. However, it has many drawbacks related… read more here.
Keywords: enhancing performance; performance peg; cholesterol; polymer micelles ... See more keywords
Preparation of fluorescent conjugated polymer micelles with multi-color emission for latent fingerprint imaging
Sign Up to like & getrecommendations! Published in 2021 at "Colloids and Surfaces A: Physicochemical and Engineering Aspects"
DOI: 10.1016/j.colsurfa.2021.126192
Abstract: Abstract The development of novel imaging agents for fluorescence detection of latent fingerprint is still important for criminal investigation and identity recognition. Herein, we reported a simple and robust method to prepare multi-color conjugated polymer… read more here.
Keywords: fingerprint; conjugated polymer; polymer micelles; multi color ... See more keywords
The Weak Link: Optimization of the Ligand-Nanoparticle Interface To Enhance Cancer Cell Targeting by Polymer Micelles.
Sign Up to like & getrecommendations! Published in 2017 at "Nano letters"
DOI: 10.1021/acs.nanolett.7b02225
Abstract: Many promising targeting ligands are hydrophobic peptides, and these ligands often show limited accessibility to receptors, resulting in suboptimal targeting. A systematic study to elucidate the rules for the design of linkers that optimize their… read more here.
Keywords: polymer micelles; nanoparticle; cancer; enhance ... See more keywords
Nano-encapsulation of halofuginone hydrobromide enhances anticoccidial activity against Eimeria tenella in chickens.
Sign Up to like & getrecommendations! Published in 2023 at "Biomaterials science"
DOI: 10.1039/d2bm01543a
Abstract: Coccidiosis is a worldwide epidemic intestinal disease with high incidence, which causes huge economic losses. Halofuginone hydrobromide (HF) is widely applied as an effective anticoccidial drug in the poultry industry. However, its therapeutic efficacy is… read more here.
Keywords: tenella; polymer micelles; halofuginone hydrobromide; nano encapsulation ... See more keywords
Destruction of Pseudomonas aeruginosa pre-formed biofilms by cationic polymer micelles bearing silver nanoparticles
Sign Up to like & getrecommendations! Published in 2020 at "Biofouling"
DOI: 10.1080/08927014.2020.1799354
Abstract: Abstract Pseudomonas aeruginosa is an opportunistic Gram-negative pathogen often associated with biofilm infections. This study evaluated the capacity for biofilm destruction of a novel combination of cationic polymer micelles formed from poly(2-(dimethylamino)ethyl methacrylate)-b-poly(ε-caprolactone)-b-poly(2-(dimethylamino)ethyl methacrylate) (PDMAEMA-PCL-PDMAEMA)… read more here.
Keywords: silver nanoparticles; pseudomonas aeruginosa; polymer micelles; cationic polymer ... See more keywords
Preparation of Pinocembrin-Loaded F127/MPEG-PDLLA Polymer Micelles and Anti-Osteoporotic Activity
Sign Up to like & getrecommendations! Published in 2022 at "AAPS PharmSciTech"
DOI: 10.1208/s12249-022-02427-1
Abstract: Pinocembrin (PCB) is 5,7-dihydroxyl flavanone and has multiple pharmacological activities, namely, anti-inflammation, anti-osteoporotic, and so on. However, low water solubility and bioavailability have hindered its application. Herein, we aimed to increase its bioavailability through preparation… read more here.
Keywords: polymer micelles; pcb; f127 mpeg; mpeg pdlla ... See more keywords
Design of Dual-Targeted pH-Sensitive Hybrid Polymer Micelles for Breast Cancer Treatment: Three Birds with One Stone
Sign Up to like & getrecommendations! Published in 2023 at "Pharmaceutics"
DOI: 10.3390/pharmaceutics15061580
Abstract: Breast cancer has a high prevalence in the world and creates a substantial socio-economic impact. Polymer micelles used as nano-sized polymer therapeutics have shown great advantages in treating breast cancer. Here, we aim to develop… read more here.
Keywords: polymer micelles; hppf micelles; breast cancer; treatment ... See more keywords