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Calculation of drug‐polymer mixing enthalpy as a new screening method of precipitation inhibitors for supersaturating pharmaceutical formulations

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0 Published in 2019 at "European Journal of Pharmaceutical Sciences"

DOI: 10.1016/j.ejps.2019.03.006

Abstract: ABSTRACT Supersaturating formulations are widely used to improve the oral bioavailability of poorly soluble drugs. However, supersaturated solutions are thermodynamically unstable and such formulations often must include a precipitation inhibitor (PI) to sustain the increased… read more here.

Keywords: precipitation; drug polymer; mixing enthalpy; polymer mixing ... See more keywords