Single-Chain Polymer Models Incorporating the Effects of Side Groups: An Approach to General Polymer Models
Sign Up to like & getrecommendations! Published in 2019 at "Macromolecules"
DOI: 10.1021/acs.macromol.9b01542
Abstract: High elasticity is one of the most important characteristics of polymers. The entropy-driven elastic behavior dominates the low force regime. The entropic elasticity of single polymer chains can be... read more here.
Keywords: incorporating effects; models incorporating; polymer models; polymer ... See more keywords
Polymer models are a versatile tool to study chromatin 3D organization.
Sign Up to like & getrecommendations! Published in 2021 at "Biochemical Society transactions"
DOI: 10.1042/bst20201004
Abstract: The development of new experimental technologies is opening the way to a deeper investigation of the three-dimensional organization of chromosomes inside the cell nucleus. Genome architecture is linked to vital functional purposes, yet a full… read more here.
Keywords: models versatile; physics; organization; versatile tool ... See more keywords
Polymer models reveal how chromatin modification can modulate force at the kinetochore
Sign Up to like & getrecommendations! Published in 2022 at "Molecular Biology of the Cell"
DOI: 10.1091/mbc.e22-02-0041
Abstract: A key feature of chromosome segregation is the ability to sense tension between sister kinetochores. DNA between sister kinetochores must be packaged in a way that sustains tension propagation from one kinetochore to its sister,… read more here.
Keywords: sister; models reveal; reveal chromatin; sister kinetochores ... See more keywords
Magnetic polymer models for epigenetics-driven chromosome folding.
Sign Up to like & getrecommendations! Published in 2019 at "Physical review. E"
DOI: 10.1103/physreve.100.052410
Abstract: Epigenetics is a driving force of important and ubiquitous phenomena in nature such as cell differentiation or even metamorphosis. Opposite to its widespread role, understanding the biophysical principles that allow epigenetics to control and rewire… read more here.
Keywords: epigenetics driven; driven chromosome; polymer models; magnetic polymer ... See more keywords
Statistics of randomly cross-linked polymer models to interpret chromatin conformation capture data.
Sign Up to like & getrecommendations! Published in 2017 at "Physical Review E"
DOI: 10.1103/physreve.96.012503
Abstract: Polymer models are used to describe chromatin, which can be folded at different spatial scales by binding molecules. By folding, chromatin generates loops of various sizes. We present here a statistical analysis of the randomly… read more here.
Keywords: capture data; cross linked; polymer models; conformation capture ... See more keywords
Polymer Models of Chromatin Imaging Data in Single Cells
Sign Up to like & getrecommendations! Published in 2022 at "Algorithms"
DOI: 10.3390/a15090330
Abstract: Recent super-resolution imaging technologies enable tracing chromatin conformation with nanometer-scale precision at the single-cell level. They revealed, for example, that human chromosomes fold into a complex three-dimensional structure within the cell nucleus that is essential… read more here.
Keywords: single cells; models chromatin; data single; chromatin imaging ... See more keywords