pH‐Responsive Polymer Nanoparticles for Efficient Delivery of Cas9 Ribonucleoprotein With or Without Donor DNA
Sign Up to like & getrecommendations! Published in 2022 at "Advanced Materials"
DOI: 10.1002/adma.202110618
Abstract: Clustered regularly interspaced short palindromic repeat (CRISPR)‐associated protein 9 (Cas9) may offer new therapeutics for genetic diseases through gene disruption via nonhomologous end joining (NHEJ) or gene correction via homology‐directed repair (HDR). However, clinical translation… read more here.
Keywords: responsive polymer; efficient delivery; donor dna; cas9 ribonucleoprotein ... See more keywords
Semiconducting Polymer Nanoparticles with Surface‐Mimicking Protein Secondary Structure as Lysosome‐Targeting Chimaeras for Self‐Synergistic Cancer Immunotherapy
Sign Up to like & getrecommendations! Published in 2022 at "Advanced Materials"
DOI: 10.1002/adma.202203309
Abstract: Immunotherapy has received tremendous attention for tumor treatment, but the efficacy is greatly hindered by insufficient tumor‐infiltration of immune cells and immunosuppressive tumor microenvironment. The strategy that can efficiently activate cytotoxic T lymphocytes and inhibit… read more here.
Keywords: semiconducting polymer; immunotherapy; protein secondary; polymer nanoparticles ... See more keywords
Recent Advances of Activatable Molecular Probes Based on Semiconducting Polymer Nanoparticles in Sensing and Imaging
Sign Up to like & getrecommendations! Published in 2017 at "Advanced Science"
DOI: 10.1002/advs.201600481
Abstract: Molecular probes that change their signals in response to the target of interest have a critical role in fundamental biology and medicine. Semiconducting polymer nanoparticles (SPNs) have recently emerged as a new generation of purely… read more here.
Keywords: sensing imaging; semiconducting polymer; recent advances; activatable molecular ... See more keywords
Preparation of Monodisperse Hyper‐Crosslinking Polymer Nanoparticles for Highly Efficient CO2 Adsorption
Sign Up to like & getrecommendations! Published in 2017 at "Macromolecular Chemistry and Physics"
DOI: 10.1002/macp.201700001
Abstract: A facile and novel method for the synthesis of monodisperse hyper-crosslinking polymer nanoparticles (HPNs) is reported in the combination of vesicle bilayer templating and hyper-crosslinking technology. Monodisperse polymer nanoparticles (PNs) around 61 nm are first… read more here.
Keywords: co2 adsorption; monodisperse hyper; crosslinking polymer; hyper crosslinking ... See more keywords
HPMA‐PEG Surfmers and Their Use in Stabilizing Fully Biodegradable Polymer Nanoparticles
Sign Up to like & getrecommendations! Published in 2017 at "Macromolecular Chemistry and Physics"
DOI: 10.1002/macp.201700380
Abstract: The most adopted methods to produce polymer nanoparticles (NPs) for medical and pharmaceutical applications use surfactants that are toxic and physically adsorbed to the NPs, with the risk of desorption and insurgence of side effects.… read more here.
Keywords: polymer; hpma peg; surfmers use; polymer nanoparticles ... See more keywords
Photocatalytic H2 O2 Production by Thiophene-Coupled Benzotriazole and Anthraquinone-based D-A Type Polymer Nanoparticles.
Sign Up to like & getrecommendations! Published in 2023 at "Macromolecular rapid communications"
DOI: 10.1002/marc.202300013
Abstract: In this article, we systematically report the photocatalytic generation of an important solar fuel-H2 O2 -by a thiophene-coupled anthraquinone (AQ) and benzotriazole-based donor (D)-acceptor (A) polymer (PAQBTz) nanoparticles. The visible-light active and redox-active D-A type… read more here.
Keywords: polymer; thiophene coupled; production; polymer nanoparticles ... See more keywords
Fluorescent Polymer Nanoparticles for Cell Barcoding In Vitro and In Vivo.
Sign Up to like & getrecommendations! Published in 2017 at "Small"
DOI: 10.1002/smll.201701582
Abstract: Fluorescent polymer nanoparticles for long-term labeling and tracking of living cells with any desired color code are developed. They are built from biodegradable poly(lactic-co-glycolic acid) polymer loaded with cyanine dyes (DiO, DiI, and DiD) with… read more here.
Keywords: color; fluorescent polymer; polymer; cell barcoding ... See more keywords
Molecular Engineering of Photoacoustic Performance by Chalcogenide Variation in Conjugated Polymer Nanoparticles for Brain Vascular Imaging.
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DOI: 10.1002/smll.201703732
Abstract: As conjugated polymer nanoparticles (CPNs) have attracted growing interest as photoacoustic (PA) imaging contrast agents, revelation of the relationship between the molecular structure of conjugated polymers and PA property is highly in demand. Here, three… read more here.
Keywords: photoacoustic performance; conjugated polymer; engineering photoacoustic; molecular engineering ... See more keywords
Photoacoustic Imaging and Photothermal Therapy of Semiconducting Polymer Nanoparticles: Signal Amplification and Second Near-Infrared Construction.
Sign Up to like & getrecommendations! Published in 2021 at "Small"
DOI: 10.1002/smll.202004723
Abstract: Photoacoustic (PA) imaging and photothermal therapy (PTT) have attracted extensive attention in disease diagnosis and treatment. Although many exogenous contrast agents have been developed for PA imaging and PTT, the design guidelines to amplify their… read more here.
Keywords: imaging photothermal; semiconducting polymer; photoacoustic imaging; polymer nanoparticles ... See more keywords
Agglomeration controllable reprecipitation method using solvent mixture for synthesizing conductive polymer nanoparticles
Sign Up to like & getrecommendations! Published in 2018 at "Colloid and Polymer Science"
DOI: 10.1007/s00396-018-4418-4
Abstract: AbstractConductive polymer nanoparticles (NPs) exhibit a strong tendency to agglomerate because of strong interactions between the π electrons in the polymer. The use of a surfactant to control this agglomeration is problematic because doing so… read more here.
Keywords: polymer; conductive polymer; solvent mixture; polymer nanoparticles ... See more keywords
Rheology of fresh cement pastes containing polymer nanoparticles
Sign Up to like & getrecommendations! Published in 2021 at "Cement and Concrete Research"
DOI: 10.1016/j.cemconres.2021.106419
Abstract: Abstract Influences of polymer nanoparticles (PNPs) with varied charge densities on the rheological behaviors of fresh cement pastes (fcps) without and with polycarboxylate superplasticizer (PCE) were studied. In the blank fcp, the addition of PCE… read more here.
Keywords: fresh cement; pce; polymer nanoparticles; cement ... See more keywords