Well-defined Mannosylated Polymer for Peptide Vaccine Delivery with Enhanced Antitumor Immunity.
Sign Up to like & getrecommendations! Published in 2021 at "Advanced healthcare materials"
DOI: 10.1002/adhm.202101651
Abstract: Peptide-based cancer vaccines offer production and safety advantages but have had limited clinical success due to their intrinsic instability, rapid clearance, and low cellular uptake. Nanoparticle-based delivery vehicles can improve the in vivo stability and… read more here.
Keywords: peptide; antitumor immunity; well defined; delivery ... See more keywords
Atomistic Molecular Dynamics Simulations of ABA-Type Polymer Peptide Conjugates: Insights into Supramolecular Structures and their Circular Dichroism Spectra.
Sign Up to like & getrecommendations! Published in 2024 at "Macromolecular rapid communications"
DOI: 10.1002/marc.202400149
Abstract: A combination of atomistic molecular dynamics (aMD) simulations and circular dichroism (CD) analysis is used to explore supramolecular structures of amphiphilic ABA-type triblock polymer peptide conjugates (PPC). Using the example of a recently introduced PPC… read more here.
Keywords: atomistic molecular; supramolecular structures; circular dichroism; polymer peptide ... See more keywords
Thermoresponsive polymer-peptide/protein conjugates
Sign Up to like & getrecommendations! Published in 2017 at "Progress in Polymer Science"
DOI: 10.1016/j.progpolymsci.2016.12.004
Abstract: Abstract This review is focused on recent achievements in the covalent attachment of biological entities, such as oligopeptides, proteins and enzymes, to thermoresponsive synthetic polymers and the influence of conjugation on the properties of macromolecules.… read more here.
Keywords: thermoresponsive polymer; peptide protein; protein conjugates; polymer peptide ... See more keywords
Strategies for the Development of pH-Responsive Synthetic Polypeptides and Polymer-Peptide Hybrids: Recent Advancements
Sign Up to like & getrecommendations! Published in 2021 at "Polymers"
DOI: 10.3390/polym13040624
Abstract: Synthetic polypeptides and polymer-peptide hybrid materials have been successfully implemented in an array of biomedical applications owing to their biocompatibility, biodegradability and ability to mimic natural proteins. In addition, these materials have the capacity to… read more here.
Keywords: polypeptides polymer; synthetic polypeptides; responsive synthetic; polymer peptide ... See more keywords