Deciphering the intrinsically disordered characteristics of the FG-Nups through the lens of polymer physics
Sign Up to like & getrecommendations! Published in 2024 at "Nucleus"
DOI: 10.1080/19491034.2024.2399247
Abstract: ABSTRACT The nuclear pore complex (NPC) is a critical gateway regulating molecular transport between the nucleus and cytoplasm. It allows small molecules to pass freely, while larger molecules require nuclear transport receptors to traverse the… read more here.
Keywords: characteristics nups; intrinsically disordered; deciphering intrinsically; polymer physics ... See more keywords
Unveiling the Machinery behind Chromosome Folding by Polymer Physics Modeling
Sign Up to like & getrecommendations! Published in 2023 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms24043660
Abstract: Understanding the mechanisms underlying the complex 3D architecture of mammalian genomes poses, at a more fundamental level, the problem of how two or multiple genomic sites can establish physical contacts in the nucleus of the… read more here.
Keywords: machinery behind; physics; polymer; polymer physics ... See more keywords
Polymer Physics Models Reveal Structural Folding Features of Single-Molecule Gene Chromatin Conformations
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DOI: 10.3390/ijms251810215
Abstract: Here, we employ polymer physics models of chromatin to investigate the 3D folding of a 2Mb wide genomic region encompassing the human LTN1 gene, a crucial DNA locus involved in key cellular functions. Through extensive… read more here.
Keywords: folding; physics; polymer physics; physics models ... See more keywords
The Polymer Physics and Theory Section
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DOI: 10.3390/polym17212832
Abstract: The section "Polymer Physics and Theory" of Polymers has significantly grown in quality since 2023 [...]. read more here.
Keywords: physics theory; theory section; section polymer; polymer physics ... See more keywords