Identification and comparison of the porcine H1, U6, and 7SK RNA polymerase III promoters for short hairpin RNA expression
Sign Up to like & getrecommendations! Published in 2020 at "Mammalian Genome"
DOI: 10.1007/s00335-020-09838-0
Abstract: RNA polymerase III is an essential enzyme in eukaryotes for synthesis of tRNA, 5S rRNA, and other small nuclear and cytoplasmic RNAs. Thus, RNA polymerase III promoters are often used in small hairpin RNA (shRNA)… read more here.
Keywords: porcine 7sk; polymerase iii; expression; rna polymerase ... See more keywords
Snapshots of RNA polymerase III in action - a mini review.
Sign Up to like & getrecommendations! Published in 2022 at "Gene"
DOI: 10.1016/j.gene.2022.146282
Abstract: RNA polymerase (Pol) III is responsible for the transcription of tRNAs, 5S rRNA, U6 snRNA, and other non-coding RNAs. Transcription factors such as TFIIIA, -B, -C, SNAPc, and Maf1 are required for promoter recognition, promoter… read more here.
Keywords: polymerase iii; rna polymerase; pol iii; snapshots rna ... See more keywords
Organization and epigenomic control of RNA polymerase III-transcribed genes in plants.
Sign Up to like & getrecommendations! Published in 2022 at "Current opinion in plant biology"
DOI: 10.1016/j.pbi.2022.102199
Abstract: The genetic information linearly scripted in chromosomes is wrapped in a ribonucleoprotein complex called chromatin. The adaptation of its compaction level and spatiotemporal organization refines gene expression in response to developmental and environmental cues. RNA… read more here.
Keywords: rna polymerase; organization epigenomic; polymerase iii; organization ... See more keywords
Gastric antral vascular ectasia in systemic sclerosis: Association with anti-RNA polymerase III and negative anti-nuclear antibodies.
Sign Up to like & getrecommendations! Published in 2020 at "Seminars in arthritis and rheumatism"
DOI: 10.1016/j.semarthrit.2020.06.016
Abstract: OBJECTIVE Gastric antral vascular ectasia (GAVE) is a vascular manifestation of systemic sclerosis (SSc) that can lead to iron deficiency anemia or acute gastrointestinal (GI) bleeding. We aimed to identify clinical features associated with GAVE.… read more here.
Keywords: anti rna; rna polymerase; gastric antral; polymerase iii ... See more keywords
A structural perspective of human RNA polymerase III
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DOI: 10.1080/15476286.2021.2022293
Abstract: ABSTRACT RNA polymerase III (Pol III) is a large multisubunit complex conserved in all eukaryotes that plays an essential role in producing a variety of short non-coding RNAs, such as tRNA, 5S rRNA and U6… read more here.
Keywords: pol iii; microscopy; polymerase iii; rna polymerase ... See more keywords
Site-directed biochemical analyses reveal that the switchable C-terminus of Rpc31 contributes to RNA polymerase III transcription initiation
Sign Up to like & getrecommendations! Published in 2022 at "Nucleic Acids Research"
DOI: 10.1093/nar/gkac1163
Abstract: Abstract Rpc31 is a subunit in the TFIIE-related Rpc82/34/31 heterotrimeric subcomplex of Saccharomyces cerevisiae RNA polymerase III (pol III). Structural analyses of pol III have indicated that the N-terminal region of Rpc31 anchors on Rpc82… read more here.
Keywords: transcription; rna polymerase; region; rpc31 ... See more keywords
A data-driven approach finds RNA polymerase III antibody and tendon friction rubs as enrichment tools for early diffuse scleroderma trials.
Sign Up to like & getrecommendations! Published in 2022 at "Rheumatology"
DOI: 10.1093/rheumatology/keac501
Abstract: OBJECTIVE Clinical trials in early diffuse systemic sclerosis (SSc) have consistently shown a placebo group response with a declining modified Rodnan skin score (mRSS), with negative outcomes. Our objective was to identify strategies using clinical… read more here.
Keywords: friction rubs; rna polymerase; enrichment; tendon friction ... See more keywords
RNA polymerase III-positive systemic sclerosis in a patient with circumscribed morphea.
Sign Up to like & getrecommendations! Published in 2017 at "Rheumatology"
DOI: 10.1093/rheumatology/kex225
Abstract: A 51-year-old male with an 11-year history of stable circumscribed plaque morphea presented with a progressive, pruritic skin rash poorly responsive to topical corticosteroids and oral antihistamines. Physical examination demonstrated multiple shiny, indurated patches with… read more here.
Keywords: sclerosis; rna polymerase; patient circumscribed; polymerase iii ... See more keywords
Local features determine Ty3 targeting frequency at RNA polymerase III transcription start sites.
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DOI: 10.1101/gr.240861.118
Abstract: Retroelement integration into host genomes affects both genome structure and function. A goal of a considerable number of investigations is to elucidate host features that influence insertion site selection. The retrotransposon Ty3 of Saccharomyces cerevisiae… read more here.
Keywords: targeting frequency; frequency; rna polymerase; start sites ... See more keywords
Anti-RNA polymerase III antibodies in patients with suspected and definite systemic sclerosis: Why and how to screen
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Scleroderma and Related Disorders"
DOI: 10.1177/2397198318786158
Abstract: Anti-RNA Polymerase III antibodies are the most frequent anti-nuclear antibodies in systemic sclerosis, after anti-centromere and anti-Topoisomerase I. Considering their specificity for systemic sclerosis, they have been included in 2013 American College of Rheumatology/European League… read more here.
Keywords: sclerosis; iii antibodies; rna polymerase; anti rna ... See more keywords
Epigenetic regulation of noncoding RNA transcription by mammalian RNA polymerase III.
Sign Up to like & getrecommendations! Published in 2017 at "Epigenomics"
DOI: 10.2217/epi-2016-0108
Abstract: RNA polymerase III (Pol III) synthesizes a range of medium-sized noncoding RNAs (collectively 'Pol III genes') whose early established biological roles were so essential that they were considered 'housekeeping genes'. Besides these fundamental functions, diverse… read more here.
Keywords: iii; iii genes; rna polymerase; pol iii ... See more keywords