Influence of polymeric excipients on the solubility of aspirin: Experimental measurement and model prediction
Sign Up to like & getrecommendations! Published in 2020 at "Fluid Phase Equilibria"
DOI: 10.1016/j.fluid.2019.112450
Abstract: Abstract In this work, the solubility of aspirin at 293.15–313.15 K was measured in several aqueous systems where one excipient out of PEG 6000, PEG 400, PVP K25, HPMC E3 and poloxamer 188 was present. It… read more here.
Keywords: solubility aspirin; influence polymeric; model; solubility ... See more keywords
The influence of polymeric excipients on desupersaturation profiles of active pharmaceutical ingredients. 1: Polyethylene glycol.
Sign Up to like & getrecommendations! Published in 2020 at "International journal of pharmaceutics"
DOI: 10.1016/j.ijpharm.2020.119317
Abstract: Polymeric excipients have proven to be beneficial in stabilizing supersaturated solutions of poorly soluble active pharmaceutical ingredients (APIs). They are therefore considered an important tool in improving oral bioavailability of such APIs. To better understand… read more here.
Keywords: crystal growth; active pharmaceutical; polymeric excipients; desupersaturation ... See more keywords