P0724ASSOCIATIONS OF URINARY POLYMERIC IMMUNOGLOBULIN RECEPTOR PEPTIDES IN THE CONTEXT OF CARDIO-RENAL SYNDROM
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DOI: 10.1093/ndt/gfaa142.p0724
Abstract: The polymeric immunoglobulin receptor (pIgR) which transports immunoglobulins from the basolateral to the apical surface of epithelial cells was recently shown to be associated with kidney dysfunction. The immune defense is initiated at the apical… read more here.
Keywords: pigr; polymeric immunoglobulin; cardio renal; immunoglobulin receptor ... See more keywords
Expression characteristics of polymeric immunoglobulin receptor in Bactrian camel (Camelus bactrianus) lungs
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DOI: 10.1371/journal.pone.0264815
Abstract: Polymeric immunoglobulin receptor (pIgR), the transmembrane transporter of polymeric immunoglobulin A and M, has multiple immune functions. To explore the characteristics of pIgR expression in Bactrian camel lungs, twelve healthy adult (2–7 years old) Bactrian… read more here.
Keywords: bactrian camel; expression; immunoglobulin receptor; polymeric immunoglobulin ... See more keywords
Evolutionary analyses of polymeric immunoglobulin receptor (pIgR) in the mammals reveals an outstanding mutation rate in the lagomorphs
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DOI: 10.3389/fimmu.2022.1009387
Abstract: Background The transcytosis of polymeric immunoglobulins, IgA and IgM, across the epithelial barrier to the luminal side of mucosal tissues is mediated by the polymeric immunoglobulin receptor (pIgR). At the luminal side the extracellular ligand… read more here.
Keywords: pigr; immunoglobulin receptor; polymeric immunoglobulin; receptor pigr ... See more keywords
Polymeric immunoglobulin receptor suppresses colorectal cancer through the AKT-FOXO3/4 axis by downregulating LAMB3 expression
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DOI: 10.3389/fonc.2022.924988
Abstract: Colorectal cancer (CRC) remains one of the most common malignancies worldwide and its mechanism is unclear. Polymeric immunoglobulin receptor (PIGR) which plays an important role in mucosal immunity is widely expressed in the mucosal epithelium… read more here.
Keywords: pigr; foxo3 axis; immunoglobulin receptor; polymeric immunoglobulin ... See more keywords
Polymeric immunoglobulin receptor (PIGR) exerts oncogenic functions via activating ribosome pathway in hepatocellular carcinoma
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DOI: 10.7150/ijms.49790
Abstract: Objective: This report aimed to investigate the potential mechanism of polymeric immunoglobulin receptor (PIGR) in promoting cancer development in hepatocellular carcinoma (HCC). Methods: PIGR expression was investigated in Gene Expression Omnibus (GEO), Oncomine, The Cancer… read more here.
Keywords: receptor pigr; polymeric immunoglobulin; group; immunoglobulin receptor ... See more keywords