An Integrated Tumor Microenvironment Responsive Polymeric Micelle for Smart Drug Delivery and Effective Drug Release.
Sign Up to like & getrecommendations! Published in 2021 at "Bioconjugate chemistry"
DOI: 10.1021/acs.bioconjchem.1c00385
Abstract: Tumor microenvironment (TME) responsive polymeric micelles are promising carriers for drug delivery. In order to meet the needs of various applications, multifarious TME-responsive switches are used to construct smart polymeric micelles, which causes the complexity… read more here.
Keywords: tme responsive; responsive polymeric; delivery; drug ... See more keywords
Cheminformatics-driven discovery of polymeric micelle formulations for poorly soluble drugs
Sign Up to like & getrecommendations! Published in 2019 at "Science Advances"
DOI: 10.1126/sciadv.aav9784
Abstract: Computer-assisted strategy for drug delivery leads to discovery of polymeric micelle formulations for poorly soluble drugs. Many drug candidates fail therapeutic development because of poor aqueous solubility. We have conceived a computer-aided strategy to enable… read more here.
Keywords: poorly soluble; discovery polymeric; soluble drugs; drug ... See more keywords
Recent Advances in Drug Delivery of Polymeric Nano-Micelles.
Sign Up to like & getrecommendations! Published in 2017 at "Current drug metabolism"
DOI: 10.2174/1389200217666160921143616
Abstract: In clinical studies, drugs with hydrophobic characteristic usually reflect low bioavailability, poor drug absorption, and inability to achieve the therapeutic concentration in blood. The production of poor solubility drugs, in abundance, by pharmaceutical industries calls… read more here.
Keywords: advances drug; drug delivery; delivery polymeric; drug ... See more keywords
Development and Evaluation of a Water Soluble Fluorometholone Eye Drop Formulation Employing Polymeric Micelle
Sign Up to like & getrecommendations! Published in 2018 at "Pharmaceutics"
DOI: 10.3390/pharmaceutics10040208
Abstract: Low aqueous solubility of drug causes difficulties in preparation and inconvenience of administration. Polymeric micelles of fluorometholone (FML) using solid dispersion technique were prepared to develop an eye drop formulation with enhanced water solubility. Solid… read more here.
Keywords: drop formulation; micelle; water; eye drop ... See more keywords