Reactive Oxygen Species‐Triggered Hydrogen Sulfide Release and Cancer‐Selective Antiproliferative Effect of Anethole Dithiolethione‐Containing Polymeric Micelles
Sign Up to like & getrecommendations! Published in 2022 at "Advanced Healthcare Materials"
DOI: 10.1002/adhm.202201836
Abstract: Hydrogen sulfide (H2S) is a gaseous signaling molecule in the human body and has attracted attention in cancer therapy due to its regulatory roles in cancer cell proliferation and migration. Accumulating evidence suggests that continuous… read more here.
Keywords: anethole dithiolethione; polymeric micelles; release; hydrogen sulfide ... See more keywords
Polymeric Micelles and Vesicles in Polyelectrolyte Multilayers: Introducing Hierarchy and Compartmentalization
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DOI: 10.1002/admi.201600317
Abstract: The incorporation of functional colloidal building blocks into polyelectrolyte multilayers provides the films with a higher level of hierarchy and separate compartments. The simplicity of the layer-by-layer approach meets the complexity of supramolecular aggregates, such… read more here.
Keywords: vesicles polyelectrolyte; introducing hierarchy; polyelectrolyte multilayers; polymeric micelles ... See more keywords
Monitoring EPR Effect Dynamics during Nanotaxane Treatment with Theranostic Polymeric Micelles
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DOI: 10.1002/advs.202103745
Abstract: Cancer nanomedicines rely on the enhanced permeability and retention (EPR) effect for efficient target site accumulation. The EPR effect, however, is highly heterogeneous among different tumor types and cancer patients and its extent is expected… read more here.
Keywords: epr effect; effect; accumulation; polymeric micelles ... See more keywords
Artificial Cellulosome Complex from the Self‐Assembly of Ni‐NTA‐Functionalized Polymeric Micelles and Cellulases
Sign Up to like & getrecommendations! Published in 2019 at "ChemBioChem"
DOI: 10.1002/cbic.201900061
Abstract: Polymer–protein core–shell nanoparticles have been explored for enzyme immobilization. This work reports on the development of functional polymeric micelles for immobilizing His6‐tagged cellulases with controlled spatial orientation of enzymes, resulting in “artificial cellulosomes” for effective… read more here.
Keywords: cellulosome complex; complex self; artificial cellulosome; nta functionalized ... See more keywords
Polymeric Micelles Loading Proteins through Concurrent Ion Complexation and pH-Cleavable Covalent Bonding for In Vivo Delivery.
Sign Up to like & getrecommendations! Published in 2019 at "Macromolecular bioscience"
DOI: 10.1002/mabi.201900161
Abstract: Protein drugs have great potential as targeted therapies, yet their application suffers from several drawbacks, such as instability, short half-life, and adverse immune responses. Thus, protein delivery approaches based on stimuli-responsive nanocarriers can provide effective… read more here.
Keywords: complexation cleavable; polymeric micelles; delivery; concurrent ion ... See more keywords
Let There be Light: Polymeric Micelles with Upper Critical Solution Temperature as Light-Triggered Heat Nanogenerators for Combating Drug-Resistant Cancer.
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DOI: 10.1002/smll.201802420
Abstract: Complete drug release and efficient drug retention are two critical factors in reversing drug resistance in cancer therapy. In this regard, polymeric micelles with an upper critical solution temperature (UCST) are designed as a new… read more here.
Keywords: drug resistance; micelles upper; upper critical; drug ... See more keywords
Drug-Dependent Morphological Transitions in Spherical and Worm-Like Polymeric Micelles Define Stability and Pharmacological Performance of Micellar Drugs.
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DOI: 10.1002/smll.202103552
Abstract: Significant advances in physicochemical properties of polymeric micelles enable optimization of therapeutic drug efficacy, supporting nanomedicine manufacturing and clinical translation. Yet, the effect of micelle morphology on pharmacological efficacy is not adequately addressed. This work… read more here.
Keywords: pharmacological performance; worm like; polymeric micelles; drug ... See more keywords
Photo-responsive polymeric micelles bearing ammonium salts cross-linked for efficient drug delivery
Sign Up to like & getrecommendations! Published in 2018 at "Polymer Bulletin"
DOI: 10.1007/s00289-018-2488-6
Abstract: The cationic photo-responsive polymeric micelles (mPEG-b-p(DEMA-co-MMA-CL)) with light-switchable cross-linker were designed and fabricated by atom transfer radical polymerization and quaternization. These micelles were well dispersed spherical with positive charge. The efficient release of encapsulated contents… read more here.
Keywords: responsive polymeric; cross; micelles bearing; polymeric micelles ... See more keywords
Pickering emulsions stabilized by self-assembled polymeric micelles of coumarin-containing cross-linkable amphiphilic terpolymer
Sign Up to like & getrecommendations! Published in 2018 at "Colloid and Polymer Science"
DOI: 10.1007/s00396-017-4259-6
Abstract: To elucidate the correlation between the oil-water interfacial property and emulsifying performance of polymeric micelles, the polymeric particulate emulsifiers based on the self-assembled micelles of amphiphilic poly(2-(dimethylamino)ethyl methacrylate-co-styrene-co-7-(4-vinylbenzyloxyl)-4-methylcoumarin) (PDSV) had been successfully prepared. The micelle… read more here.
Keywords: emulsifying performance; pickering emulsions; self assembled; cross ... See more keywords
Control of in vivo disposition and immunogenicity of polymeric micelles by adjusting poly(sarcosine) chain lengths on surface
Sign Up to like & getrecommendations! Published in 2017 at "Journal of Nanoparticle Research"
DOI: 10.1007/s11051-017-3936-1
Abstract: Four kinds of A3B-type amphiphilic polydepsipeptides, (poly(sarcosine))3-b-poly(l-lactic acid) (the degree of polymerization of poly(sarcosine) are 10, 33, 55, and 85; S103, S333, S553, and S853) were synthesized to prepare core-shell type polymeric micelles. Their in… read more here.
Keywords: sarcosine chain; chain lengths; poly sarcosine; polymeric micelles ... See more keywords
pH-responsive polymeric micelles with tunable aggregation-induced emission and controllable drug release
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Nanoparticle Research"
DOI: 10.1007/s11051-018-4447-4
Abstract: Stimuli-responsive polymeric micelles as a drug delivery vehicle have made important contributions to the development of controllable drug release. Here we develop pH-responsive polymeric micelles with tunable aggregation-induced emission and controllable drug release. Polymeric micelles… read more here.
Keywords: responsive polymeric; drug; drug release; controllable drug ... See more keywords