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Published in 2022 at "Advanced Healthcare Materials"
DOI: 10.1002/adhm.202201060
Abstract: Bacterial biofilms are a major healthcare concern resulting in refractory conditions such as chronic wounds, implant infections and failure, and multidrugâresistant infections. Aggressive and invasive strategies are employed to cure biofilm infections but are prone…
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Keywords:
ultrasound enhanced;
antibacterial activity;
bacterial biofilms;
polymeric nanoparticles ... See more keywords
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Published in 2022 at "Macromolecular bioscience"
DOI: 10.1002/mabi.202100528
Abstract: The synthesis of polymeric nanoparticles from a block copolymer based on poly(ethylene glycol) and a polymethacrylate containing the nucleobase analogue 2,6-diacylaminopyridine has been optimized by microfluidics to obtain homogeneous spherical micelles. Loading and delivery properties…
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Keywords:
cell;
polymeric nanoparticles;
block copolymer;
synthesis ... See more keywords
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Published in 2022 at "Small"
DOI: 10.1002/smll.202107126
Abstract: Ischemic stroke is a leading cause of death and disability and remains without effective treatment options. Improved treatment of stroke requires efficient delivery of multimodal therapy to ischemic brain tissue with high specificity. Here, this…
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Keywords:
polymeric nanoparticles;
brain;
therapy;
drug delivery ... See more keywords
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Published in 2018 at "Journal of Polymer Research"
DOI: 10.1007/s10965-018-1453-2
Abstract: The objective of the research study was to develop and characterize a biodegradable, thermo and pH dual responsive Oxaliplatin-loaded chitosan-graft-poly-N-isopropylacrylamide (CS-g-PNIPAAm) co-polymeric nanoparticles as a tumor-targeting drug delivery system. CS-g-PNIPAAm co-polymers were synthesized, characterized and…
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Keywords:
polymeric nanoparticles;
delivery;
drug;
pnipaam polymeric ... See more keywords
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Published in 2022 at "Journal of Nanoparticle Research"
DOI: 10.1007/s11051-022-05396-5
Abstract: Nanotechnology has the potential to improve the combat against life-threatening conditions. Considering the COVID-19 scenario, and future outbreaks, nanotechnology can play a pivotal role in several steps, ranging from disinfection protocols, manufacture of hospital clothes,…
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Keywords:
coronavirus disease;
polymeric nanoparticles;
nanotechnology;
nanoparticles therapeutic ... See more keywords
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Published in 2017 at "Applied Surface Science"
DOI: 10.1016/j.apsusc.2017.06.197
Abstract: Abstract Aggregation-induced emission (AIE) dyes based fluorescent polymeric nanoparticles (FNPs) have been intensively explored for biomedical applications. However, many of these AIE-active FNPs are relied on the self-assembly of amphiphilic copolymers, which are not stable…
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Keywords:
polymeric nanoparticles;
cross linked;
aggregation induced;
cross ... See more keywords
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Published in 2020 at "Applied Surface Science"
DOI: 10.1016/j.apsusc.2019.144799
Abstract: Abstract In this work, we report the first preparation of AIE-active FPNs via metal-free photo-mediated atom transfer radical polymerization (ATRP), employing 2-methacryloyloxyethyl phosphorylcholine (MPC) and benzyl methacrylate (BzMA) as the monomers. Herein, the AIE fluorogen,…
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Keywords:
preparation aie;
photo mediated;
aie active;
polymeric nanoparticles ... See more keywords
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Published in 2018 at "Biomaterials"
DOI: 10.1016/j.biomaterials.2018.02.034
Abstract: Cytotoxic T lymphocytes (CTLs) play a major role in cancer immunotherapy because of their ability to directly kill tumor cells and secrete tumor suppressive cytokines. Anticancer vaccines aim to provoke tumor-specific CTL responses, which require…
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Keywords:
polymeric nanoparticles;
immunostimulatory adjuvants;
cancer immunotherapy;
cancer ... See more keywords
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Published in 2017 at "Colloids and Surfaces A: Physicochemical and Engineering Aspects"
DOI: 10.1016/j.colsurfa.2017.08.036
Abstract: Abstract Functionalized nanoparticles (NPs) are critical to a wide-ranging of applications. The more versatile use of the NPs hinges on the capability to readily modify them to perform different functions. For example functionalized polymeric nanomaterials…
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Keywords:
absorption;
polymeric nanoparticles;
extraction recovery;
ligand carrying ... See more keywords
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Published in 2017 at "European Journal of Pharmaceutics and Biopharmaceutics"
DOI: 10.1016/j.ejpb.2017.06.030
Abstract: Graphical abstract Figure. No Caption available. HighlightsNovel predictive model for nanoparticle size based on the polymer properties.Polymer properties controlling particle size of nanoparticles were identified.This model reduces number of preliminary experiments in formulation development.Prediction error…
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Keywords:
polymeric nanoparticles;
particle size;
size;
model ... See more keywords
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Published in 2018 at "European Polymer Journal"
DOI: 10.1016/j.eurpolymj.2018.04.032
Abstract: Abstract Candidiasis is by far the most common fungal infection in the oral cavity and locally antifungal drugs are generally considered the first line therapy. However, some antifungal drugs like Nystatin (Nys) have very short…
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Keywords:
polymeric nanoparticles;
nanoparticles strategy;
strategy improve;
bioadhesive polymeric ... See more keywords