Roles of N-glycans in the polymerization-dependent aggregation of mutant Ig-μ chains in the early secretory pathway
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DOI: 10.1038/srep41815
Abstract: The polymeric structure of secretory IgM allows efficient antigen binding and complement fixation. The available structural models place the N-glycans bound to asparagines 402 and 563 of Ig-μ chains within a densely packed core of… read more here.
Keywords: aggregation; polymerization dependent; mutant chains; dependent aggregation ... See more keywords