Combinatorial approaches in post-polymerization modification for rational development of therapeutic delivery systems.
Sign Up to like & getrecommendations! Published in 2018 at "Acta biomaterialia"
DOI: 10.1016/j.actbio.2018.04.010
Abstract: The combinatorial polymer library approach has been proven to be effective for the optimization of therapeutic delivery systems. The library of polymers with chemical diversity has been synthesized by (i) polymerization of functionalized monomers or… read more here.
Keywords: post polymerization; polymerization; delivery; therapeutic delivery ... See more keywords
Post-polymerization modification of polybenzoxazines with boronic acids supported by B–N interactions
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DOI: 10.1039/d1py00657f
Abstract: Polybenzoxazines (PBZs) were modified using the reactivity of their inherent bis(2-hydroxybenzyl)amine (BHBA) units toward boronic acids, RB(OH)2. read more here.
Keywords: post polymerization; boronic acids; polybenzoxazines boronic; polymerization modification ... See more keywords
Amphiphilic Polypeptides Obtained by the Post-Polymerization Modification of Poly(Glutamic Acid) and Their Evaluation as Delivery Systems for Hydrophobic Drugs
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DOI: 10.3390/ijms24021049
Abstract: Synthetic poly(amino acids) are a unique class of macromolecules imitating natural polypeptides and are widely considered as carriers for drug and gene delivery. In this work, we synthesized, characterized and studied the properties of amphiphilic… read more here.
Keywords: obtained post; modification poly; poly glutamic; glutamic acid ... See more keywords
Amphiphilic Polypeptides Obtained by Post-Polymerization Modification of Poly-l-Lysine as Systems for Combined Delivery of Paclitaxel and siRNA
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DOI: 10.3390/pharmaceutics15041308
Abstract: The development of effective anti-cancer therapeutics remains one of the current pharmaceutical challenges. The joint delivery of chemotherapeutic agents and biopharmaceuticals is a cutting-edge approach to creating therapeutic agents of enhanced efficacy. In this study,… read more here.
Keywords: amphiphilic polypeptides; post polymerization; poly lysine; polymerization modification ... See more keywords