Insights into the Interactions that Trigger the Primary Nucleation of Polymorphic α-Synuclein Dimers.
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DOI: 10.1021/acschemneuro.1c00754
Abstract: Parkinson's disease is associated with the accumulation of α-synuclein (AS) aggregates that include polymorphic AS oligomers and polymorphic fibrils. There have been advances in solving the polymorphic state of AS fibrils, both by experimental techniques… read more here.
Keywords: nucleation; insights interactions; synuclein; trigger primary ... See more keywords