A 35-year effective treatment of catecholaminergic polymorphic ventricular tachycardia with propafenone
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DOI: 10.1016/j.hrcr.2018.04.003
Abstract: Key Teaching Points • Despite proven catecholaminergic polymorphic ventricular tachycardia (CPVT) with pathogen RyR2 mutation and recurrent syncope, patients could have a favorable long-term outcome over 35 years under treatment. • Propafenone could be effective… read more here.
Keywords: ventricular tachycardia; effective treatment; polymorphic ventricular; treatment ... See more keywords
Scared to death—A novel mutation in catecholaminergic polymorphic ventricular tachycardia
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DOI: 10.1016/j.hrcr.2020.01.009
Abstract: The decision to implant an implantable cardioverter-defibrillator in patients with CPVT is challenging, as there are no randomized controlled Introduction Catecholaminergic polymorphic ventricular tachycardia (CPVT) is a rare familial cardiac arrhythmia that results in bidirectional… read more here.
Keywords: death; ventricular tachycardia; polymorphic ventricular; catecholaminergic polymorphic ... See more keywords
Syncope after successful implantation of atrioventricular synchronous leadless pacemaker caused by polymorphic ventricular tachycardia
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DOI: 10.1016/j.hrcr.2020.05.003
Abstract: Introduction Leadless pacing is an alternative to transvenous single-chamber ventricular pacing (VVI/R) with a favorable safety and efficacy profile in selected patients. Until recently, the Micra (Model MC1VR01; Medtronic Inc, Minneapolis, MN) was the only… read more here.
Keywords: ventricular tachycardia; polymorphic ventricular; leadless; implantation ... See more keywords
Hypokalemia unmasking underlying premature ventricular contraction induced polymorphic ventricular tachycardia: Low potassium is not always the culprit!
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DOI: 10.1016/j.ipej.2019.12.006
Abstract: Hypokalemia is prevalent in patients resuscitated from out-of-hospital cardiac arrest and can contribute to polymorphic ventricular tachycardia (PMVT) by prolonging the QT interval. We present an interesting scenario of malignant ventricular arrythmia initially attributed to… read more here.
Keywords: potassium; ventricular tachycardia; polymorphic ventricular; hypokalemia unmasking ... See more keywords
SHORT OR LONG: POLYMORPHIC VENTRICULAR TACHYCARDIA ORIGINATING FROM THE PURKINJE SYSTEM
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DOI: 10.1016/s0735-1097(20)33878-x
Abstract: Short coupled variant of Torsades de pointes(TdP) may be responsible for sudden cardiac death in the absence of structural heart disease. Differentiation of this entity from Long QT associated TdP has important therapeutic implications. A… read more here.
Keywords: tachycardia originating; ventricular tachycardia; long polymorphic; polymorphic ventricular ... See more keywords
Documenting the descent – remote monitoring and adult-onset Catecholaminergic Polymorphic Ventricular Tachycardia associated with ventricular fibrillation and bradycardia
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DOI: 10.1017/s1047951121002377
Abstract: Abstract This image highlights a 38-year-old female with ventricular fibrillation and spontaneous return to sinus rhythm found on an implantable loop recorder inserted for recurrent syncope. Ultimately, she was diagnosed with catecholaminergic polymorphic ventricular tachycardia,… read more here.
Keywords: ventricular tachycardia; polymorphic ventricular; catecholaminergic polymorphic; ventricular fibrillation ... See more keywords
Catecholaminergic Polymorphic Ventricular Tachycardia.
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DOI: 10.1097/01.pec.0000520710.58614.76
Abstract: Catecholaminergic polymorphic ventricular tachycardia (CPVT) is a condition characterized by an abnormal heart rhythm (arrhythmia). As the heart rate increases in response to physical activity or emotional stress, it can trigger an abnormally fast and… read more here.
Keywords: polymorphic ventricular; catecholaminergic polymorphic; ventricular tachycardia; tachycardia ... See more keywords
A gain of function ryanodine receptor 2 mutation (R1760W‐RyR2) in catecholaminergic polymorphic ventricular tachycardia
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DOI: 10.1111/1440-1681.13722
Abstract: Catecholaminergic polymorphic ventricular tachycardia (CPVT) is an inherited arrhythmia syndrome associated with Ca2+ leak predominantly caused by ryanodine receptor 2 (RyR2) mutations. We identified a R1760W‐RyR2 mutation located between the N‐terminal domain and the central… read more here.
Keywords: polymorphic ventricular; catecholaminergic polymorphic; r1760w ryr2; ryr2 ... See more keywords
Efficacy of RyR2 inhibitor EL20 in induced pluripotent stem cell‐derived cardiomyocytes from a patient with catecholaminergic polymorphic ventricular tachycardia
Sign Up to like & getrecommendations! Published in 2021 at "Journal of Cellular and Molecular Medicine"
DOI: 10.1111/jcmm.16521
Abstract: Catecholaminergic polymorphic ventricular tachycardia (CPVT) is an inherited cardiac arrhythmia syndrome that often leads to sudden cardiac death. The most common form of CPVT is caused by autosomal‐dominant variants in the cardiac ryanodine receptor type‐2… read more here.
Keywords: el20; ventricular tachycardia; polymorphic ventricular; ryr2 ... See more keywords
Nationwide experience of catecholaminergic polymorphic ventricular tachycardia caused by RyR2 mutations
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DOI: 10.1136/heartjnl-2016-310509
Abstract: Objective The aim of this study was to characterise disease penetrance, course of disease and use of antiarrhythmic medication and implantable cardioverter-defibrillator (ICD) therapy in a Danish nationwide cohort of patients with catecholaminergic polymorphic ventricular… read more here.
Keywords: nationwide experience; ventricular tachycardia; polymorphic ventricular; disease ... See more keywords
Antiarrhythmic Effects of Carvedilol and Flecainide in Cardiomyocytes Derived from Catecholaminergic Polymorphic Ventricular Tachycardia Patients
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DOI: 10.1155/2018/9109503
Abstract: Mutations in the cardiac ryanodine receptor (RYR2) are the leading cause for catecholaminergic polymorphic ventricular tachycardia (CPVT). In this study, we evaluated antiarrhythmic efficacy of carvedilol and flecainide in CPVT patient-specific induced pluripotent stem cell-derived… read more here.
Keywords: carvedilol flecainide; ventricular tachycardia; polymorphic ventricular; ipsc cms ... See more keywords