Exploring the polymorphism, conformational dynamics and function of amyloidogenic peptides and proteins by temperature and pressure modulation.
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DOI: 10.1016/j.bpc.2020.106506
Abstract: Our understanding of amyloid structures and the mechanisms by which disease-associated peptides and proteins self-assemble into these fibrillar aggregates, has advanced considerably in recent years. It is also established that amyloid fibrils are generally polymorphic.… read more here.
Keywords: polymorphism conformational; exploring polymorphism; peptides proteins; temperature pressure ... See more keywords