Articles with "polymorphism ligand" as a keyword



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Polymorphism and Ligand Binding Modulate Fast Dynamics of Human Telomeric G-Quadruplexes

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Published in 2023 at "International Journal of Molecular Sciences"

DOI: 10.3390/ijms24054280

Abstract: Telomeric G-quadruplexes (G4s) are promising targets in the design and development of anticancer drugs. Their actual topology depends on several factors, resulting in structural polymorphism. In this study, we investigate how the fast dynamics of… read more here.

Keywords: polymorphism; polymorphism ligand; telomeric quadruplexes; ligand binding ... See more keywords