Inflammation and endothelial function-related gene polymorphisms are associated with carotid atherosclerosis-A study of community population in Southwest China.
Sign Up to like & getrecommendations! Published in 2023 at "Brain and behavior"
DOI: 10.1002/brb3.3045
Abstract: OBJECTIVES To investigate the relationships between 18 single nucleotide polymorphisms with carotid atherosclerosis and whether interactions among these genes were associated with an increased risk of carotid atherosclerosis. METHODS Face-to-face surveys were conducted with individuals… read more here.
Keywords: polymorphisms associated; carotid atherosclerosis; inflammation endothelial; endothelial function ... See more keywords
Regional distribution of polymorphisms associated to the disease-causing gene of spinocerebellar ataxia type 3
Sign Up to like & getrecommendations! Published in 2024 at "Journal of Neurology"
DOI: 10.1007/s00415-024-12829-9
Abstract: Knowledge about the distribution and frequency of the respective haplotypes on the wildtype and mutant allele is highly relevant in the context of future gene therapy clinical studies in Spinocerebellar Ataxia Type 3, the most… read more here.
Keywords: distribution; polymorphisms associated; ataxia type; spinocerebellar ataxia ... See more keywords
FSH receptor gene p. Thr307Ala and p. Asn680Ser polymorphisms are associated with the risk of polycystic ovary syndrome
Sign Up to like & getrecommendations! Published in 2017 at "Journal of Assisted Reproduction and Genetics"
DOI: 10.1007/s10815-017-0953-z
Abstract: PurposeThe purpose of this study was to investigate whether the follicle-stimulating hormone receptor (FSHR) gene p. Thr307Ala (c.919A>G, rs6165) and p. Asn680Ser (c.2039A>G, rs6166) polymorphisms are associated with susceptibility to polycystic ovary syndrome (PCOS).MethodsGenotyping was… read more here.
Keywords: ala; polymorphisms associated; polycystic ovary; genotype ... See more keywords
TNF-α –1031T/C and –863C/A polymorphisms are associated with dyslipidaemia
Sign Up to like & getrecommendations! Published in 2025 at "British Journal of Nutrition"
DOI: 10.1017/s000711452510398x
Abstract: Abstract TNF-α polymorphisms may influence dyslipidaemia, but their role remains unclear. This case–control study investigated associations between TNF-α gene polymorphisms (–1031T/C, −863C/A, −857C/T, −308G/A and −238G/A) and dyslipidaemia in 595 participants (162 cases, 433 controls)… read more here.
Keywords: 863c polymorphisms; dyslipidaemia; polymorphisms associated; associated dyslipidaemia ... See more keywords
Viral genome wide association study identifies novel hepatitis C virus polymorphisms associated with sofosbuvir treatment failure
Sign Up to like & getrecommendations! Published in 2021 at "Nature Communications"
DOI: 10.1038/s41467-021-25649-6
Abstract: Persistent hepatitis C virus (HCV) infection is a major cause of chronic liver disease, worldwide. With the development of direct-acting antivirals, treatment of chronically infected patients has become highly effective, although a subset of patients… read more here.
Keywords: genome wide; treatment; polymorphisms associated; hepatitis virus ... See more keywords
RAD52 gene polymorphisms are associated with risk of colorectal cancer in a Chinese Han population
Sign Up to like & getrecommendations! Published in 2017 at "Medicine"
DOI: 10.1097/md.0000000000008994
Abstract: Abstract Upward trends in the incidence and mortality rates of colorectal cancer (CRC) in China over the past decade mean that it is critical to improve survival outcomes for patients with this malignancy. Analysis of… read more here.
Keywords: risk; chinese han; polymorphisms associated; colorectal cancer ... See more keywords
Cytokine-polymorphisms associated with Preeclampsia: A review
Sign Up to like & getrecommendations! Published in 2022 at "Medicine"
DOI: 10.1097/md.0000000000030870
Abstract: Background: Preeclampsia (PE) is a syndromic disorder that affects 2% to 8% of pregnancies and is diagnosed principally when hypertension appears in the second-d half of pregnancy. WHO estimates the incidence of PE to be… read more here.
Keywords: polymorphisms associated; cytokine; cytokine polymorphisms; review ... See more keywords
Multispecies colour polymorphisms associated with contrasting microhabitats in two Mediterranean wrasse radiations
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Evolutionary Biology"
DOI: 10.1111/jeb.13999
Abstract: Intraspecific colour polymorphisms (CPs) present unique opportunities to study fundamental evolutionary questions, such as the link between ecology and phenotype, mechanisms maintaining genetic diversity and their putative role in speciation. Wrasses are highly diverse in… read more here.
Keywords: polymorphisms associated; ecology; multispecies colour; colour polymorphisms ... See more keywords
Novel genetic polymorphisms associated with severe malaria and under selective pressure in North-eastern Tanzania
Sign Up to like & getrecommendations! Published in 2018 at "PLoS Genetics"
DOI: 10.1371/journal.pgen.1007172
Abstract: Significant selection pressure has been exerted on the genomes of human populations exposed to Plasmodium falciparum infection, resulting in the acquisition of mechanisms of resistance against severe malarial disease. Many host genetic factors, including sickle… read more here.
Keywords: novel genetic; polymorphisms associated; genetic polymorphisms; severe malaria ... See more keywords
GABRA1 and GABRB2 Polymorphisms are Associated with Propofol Susceptibility
Sign Up to like & getrecommendations! Published in 2022 at "Pharmacogenomics and Personalized Medicine"
DOI: 10.2147/pgpm.s348170
Abstract: Purpose To explore the effect of gene polymorphisms of propofol GABAA receptor and metabolic enzyme on drug susceptibility during the induction period of general anesthesia. Patients and Methods A total of 294 female patients aged… read more here.
Keywords: polymorphisms associated; susceptibility; gabra1; gabrb2 ... See more keywords
Population-based Study of Risk Polymorphisms Associated with Vascular Disorders and Dementia
Sign Up to like & getrecommendations! Published in 2017 at "Current Genomics"
DOI: 10.2174/1389202918666170608093833
Abstract: Introduction: Cardiovascular and neurodegenerative disorders are among the major causes of mortality in the developed countries. Population studies evaluate the genetic risk, i.e. the probability of an individual carrying a specific disease-associated polymorphism. Identification of… read more here.
Keywords: vascular disorders; risk; polymorphisms associated; study ... See more keywords