Polymorphisms in CARD8 and NLRP3 are associated with extrapulmonary TB and poor clinical outcome in active TB in Ethiopia
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DOI: 10.1038/s41598-019-40121-8
Abstract: Innate immunity is a first line defense against Mycobacterium tuberculosis infection where inflammasome activation and secretion of the pro-inflammatory cytokine IL-1beta, plays a major role. Thus, genetic polymorphisms in innate immunity-related genes such as CARD8… read more here.
Keywords: outcome; card8 nlrp3; polymorphisms card8; poor clinical ... See more keywords