Articles with "polymorphisms genes" as a keyword



Investigation of polymorphisms in genes involved in estrogen metabolism in menstrual migraine.

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Published in 2017 at "Gene"

DOI: 10.1016/j.gene.2017.01.008

Abstract: Migraine is a common, disabling headache disorder, which is influenced by multiple genes and environmental triggers. After puberty, the prevalence of migraine in women is three times higher than in men and >50% of females… read more here.

Keywords: involved estrogen; migraine; menstrual migraine; polymorphisms genes ... See more keywords

Distribution of Genetic Polymorphisms of Genes Implicated in Thiopurine Drugs Metabolism

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Published in 2018 at "Therapeutic Drug Monitoring"

DOI: 10.1097/ftd.0000000000000548

Abstract: Abstract: Thiopurine-S-methyltransferase (TPMT) and inosine triphosphate pyrophosphatase (ITPA) are crucial enzymes involved in the metabolism of thiopurine drugs. Significant interethnic variation in the expression of TPMT and ITPA is caused by single nucleotide polymorphisms of… read more here.

Keywords: itpa; polymorphisms genes; thiopurine; tpmt ... See more keywords

Preliminary analysis of single-nucleotide polymorphisms in IL-10, IL-4, and IL-4Rα genes and profile of circulating cytokines in patients with gastric Cancer

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Published in 2018 at "BMC Gastroenterology"

DOI: 10.1186/s12876-018-0913-9

Abstract: BackgroundGastric Cancer is highly prevalent and deadly worldwide. In Colombia, it is the most lethal form of cancer. Some single-nucleotide polymorphisms in IL-10, IL-4, and IL-4Rα genes have been associated with an anti-inflammatory environment and… read more here.

Keywords: nucleotide polymorphisms; gastric cancer; single nucleotide; polymorphisms genes ... See more keywords

Polymorphisms in Genes Involved in Inflammation and Periodontitis: A Narrative Review

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Published in 2022 at "Biomolecules"

DOI: 10.3390/biom12040552

Abstract: Current evidence pinpoints that the variability in periodontitis traits in humans may be attributable to genetic factors. Different allelic variants can result in alterations in tissue structure, antibody responses and inflammatory mediators. Consequently, genetic variations… read more here.

Keywords: narrative review; genes involved; periodontitis; involved inflammation ... See more keywords

An Analysis of Genetic Polymorphisms in 76 Genes Related to the Development of Ovarian Tumors of Different Aggressiveness

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Published in 2024 at "International Journal of Molecular Sciences"

DOI: 10.3390/ijms252010876

Abstract: Borderline ovarian tumors (BOTS) are rare neoplasms of intermediate aggressiveness between cystadenomas and low-grade ovarian cancers (lgOvCa), which they share some molecular resemblances with. In contrast to the most frequent and well-described high-grade ovarian carcinomas… read more here.

Keywords: polymorphisms genes; analysis genetic; genetic polymorphisms; genes related ... See more keywords