Polymorphisms in the telomerase complex to predict outcome in patients (pts) with metastatic colorectal cancer (mCRC): Data from TRIBE and FIRE-3 phase III trials.
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DOI: 10.1200/jco.2019.37.4_suppl.566
Abstract: 566 Background: Telomere/telomerase interplay is involved in the regulation of genomic stability and cellular replicative potential. In CRC, shortening of telomeres promotes early steps of carcinogenesis but the prognostic role of telomere length is debated.… read more here.
Keywords: outcome; multivariable analysis; cancer; polymorphisms telomerase ... See more keywords