Functional Characterization of the Unique Terminal Thioesterase Domain from Polymyxin Synthetase.
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DOI: 10.1021/acs.biochem.6b01139
Abstract: Polymyxins remain one of the few antibiotics available for treating antibiotic resistant bacteria. Here we describe polymyxin B thioesterase which performs the final step in polymyxin B biosynthesis. Isolated thioesterase catalyzed cyclization of an N-acetylcystamine… read more here.
Keywords: characterization unique; functional characterization; unique terminal; polymyxin ... See more keywords