Kinetics and mechanistic study of polynuclear platinum(II) polypyridyl complexes; A paradigm shift in search of new anticancer agents
Sign Up to like & getrecommendations! Published in 2018 at "Inorganica Chimica Acta"
DOI: 10.1016/j.ica.2017.08.065
Abstract: Abstract This paper reports on a mechanistic interaction between mononuclear and polynuclear platinum(II) complexes viz; phenyl-dichlorido-2,2′-dipyridinylaminediaquaplatinum(II) (PtC1); di-2-pyridylaminomethylbenzenediaquaplatinum(II) (PtC2); 1,3,5-tris(2,2′dipyridylamino)-benzenehexaquaplatinum(II) (PtC3); 1,3,5-tris(2,2′dipyridylmethylamino)benzenehexaquaplatinum(II) (PtC4); and 2,4,6-tris(2,2′-dipyridylamino)-1,3,5-triazinehexaquaplatinum(II) (PtC5) with thiourea nucleophiles under pseudo-first-order conditions as a function of… read more here.
Keywords: polynuclear platinum; study; mechanistic study; study polynuclear ... See more keywords
Substitution-inert polynuclear platinum complexes and Glycosaminoglycans: A molecular dynamics study of its non-covalent interactions.
Sign Up to like & getrecommendations! Published in 2022 at "Journal of inorganic biochemistry"
DOI: 10.1016/j.jinorgbio.2022.111811
Abstract: An impressive class of formally substitution-inert polynuclear platinum complexes known as Substitution-inert Polynuclear Platinum (II) Complexes (SI-PPCs) present an attractive approach for medicinal inorganic chemistry through high-affinity non-covalent interactions with biomolecules, such as DNA and… read more here.
Keywords: substitution inert; polynuclear platinum; non covalent; covalent interactions ... See more keywords