Human Polyomavirus 9-An Emerging Cutaneous and Pulmonary Pathogen in Solid Organ Transplant Recipients.
Sign Up to like & getrecommendations! Published in 2022 at "JAMA dermatology"
DOI: 10.1001/jamadermatol.2021.5853
Abstract: Importance We describe the first report to our knowledge of cutaneous and systemic pathogenicity of human polyomavirus 9 in solid organ transplant recipients. Objective Three solid organ transplant recipients developed a widespread, progressive, violaceous, and… read more here.
Keywords: polyomavirus; human polyomavirus; transplant recipients; organ transplant ... See more keywords
Polyomavirus microRNAs circulating in biological fluids during viral persistence
Sign Up to like & getrecommendations! Published in 2017 at "Reviews in Medical Virology"
DOI: 10.1002/rmv.1927
Abstract: Increasing evidence suggests that microRNA‐mediated gene silencing, detected during exosome intercellular communication between cells, may be exploited by persistent human viruses. Recently, it has been reported that human polyomaviruses encode microRNAs that downregulate large T… read more here.
Keywords: polyomavirus micrornas; viral persistence; micrornas circulating; jcpyv bkpyv ... See more keywords
Co-infection with human polyomavirus BK enhances gene expression and replication of human adenovirus
Sign Up to like & getrecommendations! Published in 2018 at "Archives of Virology"
DOI: 10.1007/s00705-018-3810-1
Abstract: Immunocompromised patients are susceptible to multiple viral infections. Relevant interactions between co-infecting viruses might result from viral regulatory genes which trans-activate or repress the expression of host cell genes as well as the genes of… read more here.
Keywords: infection; human adenovirus; expression; polyomavirus ... See more keywords
A polyomavirus detected in American black bear (Ursus americanus).
Sign Up to like & getrecommendations! Published in 2021 at "Archives of virology"
DOI: 10.1007/s00705-021-05030-0
Abstract: Polyomaviruses are ancient DNA viruses that infect several species of animals. While recognition of the family Polyomaviridae has grown rapidly, there are few studies that consider their potential association with disease. Carnivora are a diverse… read more here.
Keywords: polyomavirus detected; detected american; ursus americanus; polyomavirus ... See more keywords
BK polyomavirus is a cause of bladder cancer.
Sign Up to like & getrecommendations! Published in 2019 at "Current opinion in virology"
DOI: 10.1016/j.coviro.2019.06.009
Abstract: In 2014, the International Agency for Research on Cancer judged Merkel cell polyomavirus (MCPyV) to be a probable human carcinogen. BK polyomavirus (BKPyV, a distant cousin of MCPyV) was ruled a possible carcinogen. In this… read more here.
Keywords: bladder cancer; polyomavirus cause; cause bladder; polyomavirus ... See more keywords
A novel pulmonary polyomavirus in alpacas (Vicugna pacos).
Sign Up to like & getrecommendations! Published in 2017 at "Veterinary microbiology"
DOI: 10.1016/j.vetmic.2017.01.005
Abstract: Viral metagenomic analysis detected a novel polyomavirus in a 6-month old female alpaca (Vicugna pacos) euthanized after a diagnosis of disseminated lymphosarcoma. The viral genome was fully sequenced, found to be similar to other polyomaviruses… read more here.
Keywords: vicugna; alpacas; novel pulmonary; polyomavirus ... See more keywords
Variant morphology and random chromosomal integration of BK polyomavirus in posttransplant urothelial carcinomas
Sign Up to like & getrecommendations! Published in 2020 at "Modern Pathology"
DOI: 10.1038/s41379-020-0489-0
Abstract: BK polyomavirus (BKPyV) causes major complications in solid organ transplant recipients but little is known about its role in the development of urothelial carcinoma (UC) during immunosuppression. Immunohistochemistry (IHC) screening for polyomavirus large T antigen… read more here.
Keywords: ltag expressing; integration; morphology; polyomavirus ... See more keywords
Occurrence and regression of BK polyomavirus associated carcinoma: a clinical and next-generation sequencing study.
Sign Up to like & getrecommendations! Published in 2018 at "Clinical science"
DOI: 10.1042/cs20180443
Abstract: Low-level BK polyomavirus (BKPyV) shedding is seen in at least 10% of seropositive immunocompetent adults. Moreover, BKPyV infection is highly prevalent amongst immunocompromised populations, yet little is known on its relationship with malignancy. We studied… read more here.
Keywords: occurrence regression; tag; polyomavirus; bkpyv ... See more keywords
A Difficult Decision: Atypical JC Polyomavirus Encephalopathy in a Kidney Transplant Recipient
Sign Up to like & getrecommendations! Published in 2017 at "Transplantation"
DOI: 10.1097/tp.0000000000001275
Abstract: Background A number of cerebral manifestations are associated with JC polyomavirus (JCPyV) which are diagnosed by detection of JCPyV in cerebrospinal fluid (CSF), often with the support of cerebral imaging. Here we present an unusual… read more here.
Keywords: kidney transplant; allograft; polyomavirus; jcpyv ... See more keywords
Inhibition of JC polyomavirus infectivity by the retrograde transport inhibitor Retro‐2.1
Sign Up to like & getrecommendations! Published in 2020 at "Microbiology and Immunology"
DOI: 10.1111/1348-0421.12851
Abstract: JC polyomavirus (JCPyV) is a common human pathogen that results in a chronic asymptomatic infection in healthy adults. Under conditions of immunosuppression, JCPyV spreads to the central nervous system and can cause the fatal demyelinating… read more here.
Keywords: retrograde transport; infection; infectivity; polyomavirus ... See more keywords
Low prevalence of Merkel cell polyomavirus in human epithelial thymic tumors
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DOI: 10.1111/1759-7714.12953
Abstract: The etiology of thymic epithelial tumors is unknown. Murine polyomavirus strain PTA has been shown to induce thymomas in mice. Recently, using diverse molecular techniques, we reported the presence of human polyomavirus 7 (HPyV7) in… read more here.
Keywords: merkel cell; prevalence merkel; cell polyomavirus; polyomavirus ... See more keywords