Component effect of stem cell-loaded thermosensitive polypeptide hydrogels on cartilage repair.
Sign Up to like & getrecommendations! Published in 2018 at "Acta biomaterialia"
DOI: 10.1016/j.actbio.2018.04.035
Abstract: Biophysical properties of the desired biomimetic scaffolds, such as porosity and elasticity, have been proven associated with the efficacy of cartilage regeneration. In this work, the copolymers of poly(l-alanine)-block-poly(ethylene glycol)-block-poly(l-alanine) (PA-PEG-PA) and poly(l-alanine-co-l-phenylalanine)-block-poly(ethylene glycol)-block-poly(l-alanine-co-l-phenylalanine) (PAF-PEG-PAF)… read more here.
Keywords: polypeptide hydrogels; thermosensitive polypeptide; phenylalanine; poly alanine ... See more keywords
Efficient Catalyst-Free One-Pot Synthesis of Polysaccharide-Polypeptide Hydrogels in Aqueous Solution.
Sign Up to like & getrecommendations! Published in 2024 at "Biomacromolecules"
DOI: 10.1021/acs.biomac.4c00251
Abstract: The preparation of polysaccharide-peptide hydrogels usually involves multiple synthetic steps, thus reducing the effectiveness and practicality of these approaches. Inspired by recent discoveries in aqueous N-carboxyanhydride (NCA) ring-opening polymerization (ROP) and ring-opening polymerization-induced nanogelation, we… read more here.
Keywords: polypeptide hydrogels; catalyst free; polysaccharide polypeptide; one pot ... See more keywords
Chiral polypeptide hydrogels regulating local immune microenvironment and anti-tumor immune response
Sign Up to like & getrecommendations! Published in 2025 at "Nature Communications"
DOI: 10.1038/s41467-025-56137-w
Abstract: The impact of chirality on immune response has attracted great interest in cancer vaccine research recently. However, the study of chiral synthetic polypeptide hydrogels as cancer vaccines as well as of the impact of biomaterials… read more here.
Keywords: polypeptide hydrogels; local immune; response; microenvironment ... See more keywords
Physiologically relevant pH- and temperature-responsive polypeptide hydrogels with adhesive properties
Sign Up to like & getrecommendations! Published in 2021 at "Polymer Chemistry"
DOI: 10.1039/d1py00290b
Abstract: Physiologically relevant pH- and temperature-responsive polypeptide hydrogels with adhesive properties were developed and characterized. read more here.
Keywords: hydrogels adhesive; relevant temperature; polypeptide hydrogels; responsive polypeptide ... See more keywords
Amphotericin B-conjugated polypeptide hydrogels as a novel innovative strategy for fungal infections
Sign Up to like & getrecommendations! Published in 2018 at "Royal Society Open Science"
DOI: 10.1098/rsos.171814
Abstract: The present work is focused on the design and development of novel amphotericin B (AmB)-conjugated biocompatible and biodegradable polypeptide hydrogels to improve the antifungal activity. Using three kinds of promoting self-assembly groups (2-naphthalene acetic acid… read more here.
Keywords: polypeptide hydrogels; microscopy; amb conjugated; ffdk amb ... See more keywords